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  1. Colon cancer remains one of the most common malignancies across the world. Thus far, a biomarker, which can comprehensively predict the survival outcomes, clinical characteristics, and therapeutic sensitivity,...

    Authors: Yonggan Xue, Bobin Ning, Hongyi Liu and Baoqing Jia
    Citation: BMC Gastroenterology 2022 22:127
  2. Using endoscopy as the reference, this study evaluated the accuracy of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in measuring distance from the incisors to the PET de...

    Authors: Szu-Wei Hsu, Jeffrey S. Chang, Wei-Lun Chang, Forn-Chia Lin and Nan-Tsing Chiu
    Citation: BMC Gastroenterology 2022 22:126
  3. No studies have compared the performance of microvascular and microsurface patterns alone with their combination in patients undergoing magnifying endoscopy with narrow-band imaging for diagnosing gastric canc...

    Authors: Yusuke Horiuchi, Toshiaki Hirasawa, Naoki Ishizuka, Junki Tokura, Mitsuaki Ishioka, Yoshitaka Tokai, Ken Namikawa, Shoichi Yoshimizu, Akiyoshi Ishiyama, Toshiyuki Yoshio and Junko Fujisaki
    Citation: BMC Gastroenterology 2022 22:125
  4. Serum ceruloplasmin is one of the major diagnostic parameters for Wilson’s disease (WD). Age and gender difference of serum ceruloplasmin remain controversy. This study aims to assess diagnostic value of serum...

    Authors: Xinshuo Lu, Simin Li, Wen Zhang, Yunting Lin, Zhikun Lu, Yanna Cai, Xueying Su, Yongxian Shao, Zongcai Liu, Huiying Sheng, Yonglan Huang, Li Liu and Chunhua Zeng
    Citation: BMC Gastroenterology 2022 22:124
  5. Intraoperative near-infrared fluorescence (NIR) imaging with indocyanine green (ICG) can demonstrate real-time lymphatic drainage and thus improve the accuracy and completeness of lymphadenectomy in colorectal...

    Authors: Yanwu Sun, Yu Lin, Zhun Liu, Weizhong Jiang and Pan Chi
    Citation: BMC Gastroenterology 2022 22:123
  6. The prognostic value of intratumor T regulatory cells (Tregs) in colorectal cancer (CRC) was previously reported, but the role of these cells in tumor draining lymph nodes (TDLNs) was less addressed.

    Authors: Bing Yan, Jianmei Xiong, Qianwen Ye, Tianhui Xue, Jia Xiang, Mingyue Xu, Fang Li and Wei Wen
    Citation: BMC Gastroenterology 2022 22:122
  7. Previous studies have confirmed that systemic immune-inflammatory index (SII) and prognostic nutritional index (PNI) can predict the prognosis and chemotherapy efficacy of various malignant tumors. However, to...

    Authors: Ping’an Ding, Honghai Guo, Chenyu Sun, Peigang Yang, Na Hyun Kim, Yuan Tian, Yang Liu, Pengpeng Liu, Yong Li and Qun Zhao
    Citation: BMC Gastroenterology 2022 22:121
  8. The clinical characteristics of synchronous colorectal cancer (SCRC) reported in previous studies differ significantly. Furthermore, little is known about the characteristics of early-onset synchronous colorec...

    Authors: Huaxian Chen, Shi Yin, Zhizhong Xiong, Xianzhe Li, Fengxiang Zhang, Xijie Chen, Jianping Guo, Minghao Xie, Chaobin Mao, Longyang Jin and Lei Lian
    Citation: BMC Gastroenterology 2022 22:120
  9. We aimed to find the association between gastrointestinal (GI) and respiratory symptoms with mortality and hospitalization among COVID-19 patients.

    Authors: Alireza Delavari, Samaneh Asgari, Yousef Alimohamadi, Abbass Vosoogh-Moghaddam, Anahita Sadeghi, Shokouh Shahrousvand, Armin Zakeri, Rahmatollah Moradzadeh and Samaneh Akbarpour
    Citation: BMC Gastroenterology 2022 22:119
  10. The natural history and incidence of hepatocellular carcinoma (HCC) arising from indeterminate liver lesions are not well described. We aimed to define the incidence of HCC in a cohort of patients undergoing s...

    Authors: Sara Cococcia, Priti Dutta, Melika Moghim, Brian Hogan, Sudeep Tanwar, Aileen Marshall, Douglas Macdonald, Dominic Yu, James O’Beirne, William M. Rosenberg and Paul M. Trembling
    Citation: BMC Gastroenterology 2022 22:118
  11. Studies investigating the changes in short-chain fatty acids (SCFAs) in patients with ulcerative colitis (UC) have yielded inconsistent results. We performed a meta-analysis of studies that investigated the al...

    Authors: Hao-Ming Xu, Hai-Lan Zhao, Gong-Jing Guo, Jing Xu, You-Lian Zhou, Hong-Li Huang and Yu-Qiang Nie
    Citation: BMC Gastroenterology 2022 22:117
  12. Enteric fever is a systemic disease caused by Salmonella enterica serovar Typhi or Salmonella enterica serovar Paratyphi, characterized by high fever and abdominal pain. Most patients with enteric fever improve w...

    Authors: Hong Jae Jeon, Jong Seo Lee, Byung Seok Lee, Seok Hyun Kim, Eaum Seok Lee, Jae Kyu Sung, Hee Seok Moon, Sun Hyung Kang, Hyun Seok Lee, Seongwoo Choi, Heon Sa-Kong, Shinhye Cheon and Hyuk Soo Eun
    Citation: BMC Gastroenterology 2022 22:116

    The Correction to this article has been published in BMC Gastroenterology 2022 22:230

  13. Whether primary tumor location (PTL) is predictive of survival benefits following primary tumor resection plus metastasectomy (PMTR) and primary tumor resection (PTR) alone in stage IV colorectal cancer patien...

    Authors: Yi-Chen Yao, Jun-Quan Chen, Ling Yin, Wu-Hao Lin, Jian-Hong Peng and Wen-Hua Fan
    Citation: BMC Gastroenterology 2022 22:114
  14. Most patients with coronavirus disease 2019 demonstrate liver function damage. In this study, the laboratory test data of patients with moderate coronavirus disease 2019 were used to establish and evaluate an ...

    Authors: Yiting Wang, Dandan Gao, Xuewen Li, Panyang Xu, Qi Zhou, Junguo Yin and Jiancheng Xu
    Citation: BMC Gastroenterology 2022 22:113
  15. The alfapump® is an implantable class III medical device that pumps ascitic fluid from the peritoneal space to the urinary bladder from where it is excreted. The pump reduces or abrogates the need for repeated pa...

    Authors: Niels Kristian Aagaard, Massimo Malago, Andrea De Gottardi, Michael Thomas, Gerd Sauter, Cornelius Engelmann, David Aranovich, Michal Cohen, Thierry Thévenot, Thomas Ehmann, Jeroen Capel, Paolo Angeli, Rajiv Jalan and Guido Stirnimann
    Citation: BMC Gastroenterology 2022 22:111
  16. Many older patients experience constipation as a bothersome symptom with a negative impact on quality of life. During hospitalization, the focus is often on the reason for admission with the risk that other he...

    Authors: Hanne Konradsen, Veronica Lundberg, Jan Florin and Anne-Marie Boström
    Citation: BMC Gastroenterology 2022 22:110
  17. Current study aims to determine the prognostic value of Multiparameter MRI after combined Lenvatinib and TACE therapy in patients with advanced unresectable hepatocellular carcinoma (HCC).

    Authors: Junpeng Luo, Zhimei Huang, Murong Wang, Tian Li and Jinhua Huang
    Citation: BMC Gastroenterology 2022 22:108
  18. The goal of this study was to investigate the effects of treatment with Saccharomyces boulardii and Lactobacillus reuteri on the eradication of Helicobacter pylori and Adverse effects (AEs) of the treatment.

    Authors: Nooshin Naghibzadeh, Fatemeh Salmani, Samira Nomiri and Tahmine Tavakoli
    Citation: BMC Gastroenterology 2022 22:107
  19. Gastrointestinal symptoms have been reported in patients with COVID-19. Several clinical investigations suggested that gastrointestinal symptoms were associated with disease severity of COVID-19. However, the ...

    Authors: Yang Wang, Yimin Li, Yifan Zhang, Yun Liu and Yulan Liu 
    Citation: BMC Gastroenterology 2022 22:106
  20. A randomized, placebo-controlled clinical trial (FDREST) of a novel formulation of caraway oil and L-menthol (COLM-SST) demonstrated symptom relief in patients with functional dyspepsia (FD). Two follow-up stu...

    Authors: Brian E. Lacy, William D. Chey, Michael S. Epstein, Syed M. Shah, Patrick Corsino, Linda R. Zeitzoff and Brooks D. Cash
    Citation: BMC Gastroenterology 2022 22:105
  21. Cap polyposis (CP) is a benign, non-malignant inflammatory disease that affects the rectum. It usually occurs during the 5th decade of life, but children could also be affected. Its specific pathology is unkno...

    Authors: Abdolreza Emami, Javad Shokri Shirvani, Akramasadat Hosseini and Seyed Hossein Hamidi
    Citation: BMC Gastroenterology 2022 22:104
  22. Gastric cancer (GC) is the fourth most common cancer and the third leading cancer-related cause of death worldwide since most patients are diagnosed at an advanced stage. The majority of GCs are adenocarcinoma...

    Authors: Vesna Jugovec, Jernej Benedik, Jera Jeruc and Peter Popovic
    Citation: BMC Gastroenterology 2022 22:103
  23. Given the increasing prevalence of non-alcoholic fatty liver disease, it is necessary to find an easy and cost-effective method in its management and treatment. Probiotics are a group of living microorganisms ...

    Authors: Sara Ebrahimi-Mousavi, Seyed Moayed Alavian, Amir Ali Sohrabpour, Fatemeh Dashti, Kurosh Djafarian and Ahmad Esmaillzadeh
    Citation: BMC Gastroenterology 2022 22:102
  24. Protein-losing gastroenteropathy (PLGE) is a syndrome with a chief complaint of hypoalbuminemia, which occurs due to plasma protein leakage in the gastrointestinal tract, leading to general edema, ascites, and...

    Authors: Misako Tanaka, Hideto Kawaratani, Ryuichi Noguchi, Aritoshi Koizumi, Akihiko Shibamoto, Kosuke Kaji, Naotaka Shimozato, Kuniyuki Kojima, Yoshiaki Nishimura and Hitoshi Yoshiji
    Citation: BMC Gastroenterology 2022 22:101
  25. Oral administration of health-promoting bacteria is increasingly used in clinical practise. These bacteria have anti-inflammatory characteristics and modulate the immune system without major reported side effe...

    Authors: Christina Stene, Andrada Röme, Ingrid Palmquist, Caroline Linninge, Göran Molin, Siv Ahrné, Louis Banka Johnson and Bengt Jeppsson
    Citation: BMC Gastroenterology 2022 22:100
  26. IgG4-related cholecystitis, which is a manifestation of IgG4-related disease in the gallbladder, is associated with autoimmune pancreatitis or IgG4-related sclerosing cholangitis in most cases; isolated gallbl...

    Authors: Yuko Harada, Kisyo Mihara, Ryusuke Amemiya, Masashi Nakagawa, Ryota Hanada, Kentaro Inoue, Masaya Shito, Hideki Orikasa and Koichi Aiura
    Citation: BMC Gastroenterology 2022 22:99
  27. Monocyte to lymphocyte ratio (MLR) represents a pro-inflammatory immune microenvironment. The aim of this study was to elucidate the effect of MLR and subsequent MLR when relapse occurred (R-MLR) on prognosis ...

    Authors: Qi Wang, Wenying Qiao, Biyu Liu, Jianjun Li, Chunwang Yuan, Jiang Long, Caixia Hu, Chaoran Zang, Jiasheng Zheng and Yonghong Zhang
    Citation: BMC Gastroenterology 2022 22:98
  28. Submucosal oesophageal squamous cell carcinoma is a quite infrequent and special type of oesophageal cancer. Its endoscopic manifestations are similar to those of submucosal oesophageal lesions, so it is easil...

    Authors: Yuting Jia, Quanmao Zhang, Erfeng Li, Zhen Zhang and Xing Chen
    Citation: BMC Gastroenterology 2022 22:97
  29. Portal hypertensive biliopathy (PHB) was caused by anatomical and functional abnormalities in the intrahepatic and extrahepatic bile ducts secondary to portal hypertension. Currently, there is no consensus reg...

    Authors: Ming Zhao, Xiaoze Wang, Bangxi Liu and Xuefeng Luo
    Citation: BMC Gastroenterology 2022 22:96
  30. The current guideline recommends patients who meet high probability criteria for choledocholithiasis to receive endoscopic retrograde cholangiopancreatography (ERCP). However, adverse events can occur during E...

    Authors: Meng-Ying Lin, Chun-Te Lee, Ming-Tsung Hsieh, Ming-Ching Ou, Yao-Shen Wang, Meng-Chieh Lee, Wei-Lun Chang and Bor-Shyang Sheu
    Citation: BMC Gastroenterology 2022 22:94
  31. Mucosal healing (MH) evaluated by endoscopy is a novel target of therapy in UC as it is associated with improved long-term outcomes. It is defined based on the Mayo endoscopic score (MES), but it is still to d...

    Authors: Angelo Viscido, Marco Valvano, Gianpiero Stefanelli, Annalisa Capannolo, Chiara Castellini, Eugenia Onori, Antonio Ciccone, Filippo Vernia and Giovanni Latella
    Citation: BMC Gastroenterology 2022 22:92
  32. Acute adhesion-related small bowel obstruction (ASBO) is a common digestive emergency, accounting for 1 to 3% of all digestive emergencies. The efficacy of conservative management in this setting is a subject ...

    Authors: Charles Sabbagh, Francois Mauvais, Jean-Jacques Tuech, Christophe Tresallet, Pablo Ortega-Debalon, Muriel Mathonnet, Jeremie H. Lefevre, Zaher Lakkis, David Fuks, Fabrice Muscari, Bernard Dron, Philippe Couderc, Arnaud Alves and Jean-Marc Regimbeau
    Citation: BMC Gastroenterology 2022 22:90
  33. Intestinal tuberculosis still has a high incidence, especially in developing countries. The biggest challenge of this disease is the establishment of the diagnosis because the clinical features are not typical...

    Authors: Hasan Maulahela, Marcellus Simadibrata, Erni Juwita Nelwan, Nur Rahadiani, Editha Renesteen, S. W. T. Suwarti and Yunita Windi Anggraini
    Citation: BMC Gastroenterology 2022 22:89
  34. Methylated SDC2 and TFPI2 are widely used for colorectal cancer (CRC) detection. However, they often miss some CRCs, which directly diminishes the sensitivity. Further investigations of the underlying mechanisms ...

    Authors: Ruixue Lei, Yanteng Zhao, Kai Huang, Qian Wang, Kangkang Wan, Tingting Li, Haijun Yang and Xianping Lv
    Citation: BMC Gastroenterology 2022 22:88
  35. Abnormal hypermethylation of the septin 9 gene was an inchoate incident in some cancers. Though latest several researches had paid attention to its value in prognosis, the consequences were not distinctly, esp...

    Authors: Mingliang Huang, Jiehua He, Wei Lai, Lu Liu, Heyang Xu, Yujie Zeng, Qiusheng Lan, Xiangan Lin and Zhonghua Chu
    Citation: BMC Gastroenterology 2022 22:87
  36. Authors: Luca Elli, Donatella Barisani, Valentina Vaira, Maria Teresa Bardella, Matilde Topa, Maurizio Vecchi, Luisa Doneda, Alice Scricciolo, Vincenza Lombardo and Leda Roncoroni
    Citation: BMC Gastroenterology 2022 22:86

    The original article was published in BMC Gastroenterology 2020 20:387

  37. To predict survival time of Korean hepatocellular carcinoma (HCC) patients using multi-center data as a foundation for the development of a predictive artificial intelligence model according to treatment metho...

    Authors: Byeonggwan Noh, Young Mok Park, Yujin Kwon, Chang In Choi, Byung Kwan Choi, Kwang il Seo, Yo-Han Park, Kwangho Yang, Sunju Lee, Taeyoung Ha, YunKyong Hyon and Myunghee Yoon
    Citation: BMC Gastroenterology 2022 22:85
  38. Children in low-resource settings are exposed to multiple risk factors for enteropathogens. However, the probability of exposures may be different across exposure pathways. Accordingly, this study was conducte...

    Authors: Zemichael Gizaw, Alemayehu Worku Yalew, Bikes Destaw Bitew, Jiyoung Lee and Michael Bisesi
    Citation: BMC Gastroenterology 2022 22:84
  39. Endoscopic assessment of disease activity is a key parameter in the management of ulcerative colitis. Whether sigmoidoscopy alone is sufficient to evaluate the disease activity in ulcerative colitis lacks stud...

    Authors: Su Bum Park, Seong-Jung Kim, Jun Lee, Yoo Jin Lee, Dong Hoon Baek, Geom Seog Seo, Eun Soo Kim, Sang-Wook Kim and So Yeong Kim
    Citation: BMC Gastroenterology 2022 22:83
  40. In patients with severe polycystic liver disease (PLD), there is a need for new treatments. Estrogens and possibly other female sex hormones stimulate growth in PLD. In some patients, liver volume decreases af...

    Authors: S. E. Aapkes, L. H. P. Bernts, A. P. van den Berg, M. van den Berg, H. Blokzijl, A. E. P. Cantineau, M. D. A. van Gastel, R. J. de Haas, P. Kappert, R. U. Müller, F. Nevens, R. Torra, A. Visser, J. P. H. Drenth and R. T. Gansevoort
    Citation: BMC Gastroenterology 2022 22:82
  41. The role of Helicobacter pylori (H. pylori) infection in the development of non-alcoholic fatty liver disease (NAFLD) remains controversial. The exact relationship requires further investigation. This study aimed...

    Authors: Weijun Wang, Mengke Fan, Rui Gong, Yurui Zhang, Junchao Zeng, Sanping Xu and Rong Lin
    Citation: BMC Gastroenterology 2022 22:81
  42. Acute-on-chronic liver failure (ACLF) is featured with rapid deterioration of chronic liver disease and poor short-term prognosis. Liver transplantation (LT) is recognized as the curative option for ACLF. Howe...

    Authors: Min Yang, Bo Peng, Quan Zhuang, Junhui Li, Hong Liu, Ke Cheng and Yingzi Ming
    Citation: BMC Gastroenterology 2022 22:80
  43. Colorectal cancer (CRC) consists of several histological subtypes that greatly affect prognosis. Venous invasion (VI) has been implicated in the postoperative recurrence of CRC, but the relationship between th...

    Authors: Yasuo Imai and Masanori Ichinose
    Citation: BMC Gastroenterology 2022 22:79
  44. Heterotopic tumor is a rare disease. Thus far, no cases of heterotopic cholangiocarcinoma have been reported in the world. Cholangiocarcinoma mainly metastasizes by direct invasion, and it can lead to liver me...

    Authors: Chao Wang, Baoyue Zhang, Runmei Peng, Zan Zuo, Hongzhong Cheng, Jun Zhu, Tianxing Chen and Zhengji Song
    Citation: BMC Gastroenterology 2022 22:78

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