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  1. The role of consolidative chemotherapy (CCT) for locally advanced esophageal squamous cell carcinoma (LA-ESCC) patients treated with definitive concurrent chemoradiotherapy (dCCRT) is unclear. We aimed to comp...

    Authors: Chen-Yuan Lin, Ming-Yu Lien, Chi-Ching Chen, Hsin-Yuan Fang, Yu-Sen Lin, Chien-Kuang Chen, Jian-Xun Chen, Ting-Yu Lu, Tzu-Min Huang, Te-Chun Hsieh, Shung-Shung Sun, Chia-Chin Li and Chun-Ru Chien
    Citation: BMC Gastroenterology 2022 22:381
  2. Cholestatic liver diseases are a major source of morbidity and mortality that can progress to end-stage liver disease and hyperbilirubinemia is a hallmark of cholestasis. There are few effective medical therap...

    Authors: Xiaoying Liu, Sarah A. Taylor, Stela Celaj, Josh Levitsky and Richard M. Green
    Citation: BMC Gastroenterology 2022 22:380
  3. Post-operative pain is the main problem of hemorrhoidectomy. An adequate pain management can promote early mobilization, fast recovery, and reduce hospitalization costs. This study aimed to investigate the rol...

    Authors: Imam Sofii, Handy Darmawan, Amelia Sophia Ramadhini, Fauzan Kurniawan and Ahmad Shafa Hanif
    Citation: BMC Gastroenterology 2022 22:379
  4. The stromal antigen 3 (STAG3) gene encodes an adhesion complex subunit that can regulate sister chromatid cohesion during cell division. Chromosome instability caused by STAG3 gene mutation may potentially pro...

    Authors: Menglin Zhao, Yanyan Wang, Yue Zhang, Xinwei Li, Jiaqi Mi, Qiang Wang, Zhijun Geng, Lugen Zuo, Xue Song, Sitang Ge, Zining Zhang, Mingyue Tang, Huiyuan Li, Zishu Wang, Chenchen Jiang and Fang Su
    Citation: BMC Gastroenterology 2022 22:378
  5. The natural history of intracholecystic papillary neoplasm (ICPN), especially the speed of growth from small benign to a carcinomatous lesion, is quite unrevealed. Here, we report an extremely rare case of ICP...

    Authors: Daisuke Koike, Hiroyuki Kato, Yukio Asano, Masahiro Ito, Satoshi Arakawa, Norihiko Kawabe, Masahiro Shimura, Chihiro Hayashi, Takayuki Ochi, Kenshiro Kamio, Toki Kawai, Hironobu Yasuoka, Takahiko Higashiguchi and Akihiko Horiguchi
    Citation: BMC Gastroenterology 2022 22:377
  6. Celiac disease (CD) is a genetically determined autoimmune disease triggered by gluten consumption. Patients with these conditions have intraepithelial lymphocytosis, crypt hyperplasia, and severe intestinal a...

    Authors: Mehran Ajdani, Nazanin Mortazavi, Sima Besharat, Saeed Mohammadi, Taghi Amiriani, Ahmad Sohrabi, Alireza Norouzi and Ghezeljeh Edris
    Citation: BMC Gastroenterology 2022 22:375
  7. In 2016 the World Health Organization (WHO) had adopted a global strategy to eliminate Hepatitis B (HBV) by 2030 through five core interventions. One of which is the “cascade of care”, the continuum of service...

    Authors: Zhuo-zhi Lim, Jau shya Teo, Ah-Choon Tan and Teck Onn Lim
    Citation: BMC Gastroenterology 2022 22:374
  8. Revision surgery for the complications after repair of esophageal atresia is often complex because of previous surgeries and chest infections and thus requires surgical expertise. This study describes surgical...

    Authors: Yanan Zhang, Murong Wang, Shuangshuang Li, Junmin Liao, Kaiyun Hua, Shen Yang and Jinshi Huang
    Citation: BMC Gastroenterology 2022 22:373
  9. Eccentric exhaustive exercise (EEE) training has been known as a promising training modality to enhance performance and stimulate adaptation in healthy individuals or patients that might also cause abnormal li...

    Authors: Zahra Rahimpour, Rastegar Hoseini and Nasser Behpour
    Citation: BMC Gastroenterology 2022 22:372
  10. International guidelines recommend emergency cholecystectomy for acute cholecystitis in patients who are healthy or have mild systemic disease (ASA1-2). Surgery is also an option for patients with severe syste...

    Authors: Erik Osterman, Louise Helenius, Christina Larsson, Sofia Jakobsson, Tamali Majumder, Anders Blomberg, Jennie Wickenberg and Fredrik Linder
    Citation: BMC Gastroenterology 2022 22:371
  11. Current data indicate that supplements such as folic acid and vitamin B may be beneficial in halting and even reversing atrophic gastritis, intestinal metaplasia and intraepithelial neoplasia, generally referr...

    Authors: Jing Lei, Fugang Ren, Wenyuan Li, Xiaochuan Guo, Qingsong Liu, Hongjing Gao, Yaobin Pang, Yingjie He, Jing Guo and Jinhao Zeng
    Citation: BMC Gastroenterology 2022 22:370
  12. Although the current guidelines recommend endoscopic combination therapy, endoscopic epinephrine injection (EI) monotherapy is still a simple, common and effective modality for treating peptic ulcer bleeding (...

    Authors: Shan He, Linlin Liu, Liu Ouyang, Jingsong Wang, Nonghua Lv, Youxiang Chen, Xu Shu and Zhenhua Zhu
    Citation: BMC Gastroenterology 2022 22:368
  13. Medication consumption has been suggested as a risk factor for microscopic colitis (MC), but studies of varying design have yielded inconsistent results. Our aim was to evaluate the association between medicat...

    Authors: Eugene F. Yen, Daniel B. Amusin, Janet Yoo, Asantewaa Ture, Nicole M. Gentile, Michael J. Goldberg and Jay L. Goldstein
    Citation: BMC Gastroenterology 2022 22:367
  14. The prevalence of fatty liver disease is potentially increasing in adolescents and young adults (AYAs) due to the obesity and alcohol pandemics. The aim of this study was to assess the prevalence of alcohol-as...

    Authors: Naim Alkhouri, Ashraf Almomani, Phuc Le, Julia Y. Payne, Imad Asaad, Celine Sakkal, Miriam Vos, Mazen Noureddin and Prabhat Kumar
    Citation: BMC Gastroenterology 2022 22:366
  15. Methotrexate is an immunomodulatory drug for patients with Crohn’s disease. Erythrocyte MTX-polyglutamates (MTX-PG1-5) may be used for therapeutic drug monitoring (TDM) as MTX-PG is thought to mediate MTX’s effic...

    Authors: M. M. van de Meeberg, M. L. Seinen, H. H. Fidder, M. Lin, B. Oldenburg, N. K. de Boer, G. Bouma, R. de Jonge and M. Bulatović Ćalasan
    Citation: BMC Gastroenterology 2022 22:365
  16. Stromal cells play an important role in the process of tumor progression, but the relationship between stromal cells and metabolic reprogramming is not very clear in gastric cancer (GC).

    Authors: Junyu Huo, Jing Guan and Yankun Li
    Citation: BMC Gastroenterology 2022 22:364
  17. Targeted puncture of an appropriate portal venous branch during transjugular intrahepatic portosystemic shunt (TIPS) procedure may reduce the risk of postprocedural overt hepatic encephalopathy (HE). This stud...

    Authors: Chongtu Yang, Yang Chen, Chaoyang Wang, Jiacheng Liu, Songjiang Huang, Chen Zhou, Yingliang Wang, Shuguang Ju, Tongqiang Li, Yaowei Bai, Wei Yao and Bin Xiong
    Citation: BMC Gastroenterology 2022 22:363
  18. Gastric carcinosarcoma is most frequently diagnosed at an advanced stage when the tumor is generally large with invasion into other organs, lymph node metastasis, and distant metastasis. Standard chemotherapy ...

    Authors: Hirokatsu Hayashi, Akitaka Makiyama, Naoki Okumura, Itaru Yasufuku, Chiemi Saigo, Tamotsu Takeuchi, Tatsuhiko Miyazaki, Yoshihiro Tanaka, Nobuhisa Matsuhashi, Katsutoshi Murase, Takao Takahashi, Manabu Futamura and Kazuhiro Yoshida
    Citation: BMC Gastroenterology 2022 22:360
  19. Gastric cancer ranks high in terms of morbidity and mortality worldwide. Multimodal therapy is therefore essential for locally advanced gastric cancer. Recent studies have demonstrated that both perioperative ...

    Authors: Jinming Shi, Ning Li, Yuan Tang, Liming Jiang, Lin Yang, Shulian Wang, Yongwen Song, Yueping Liu, Hui Fang, Ningning Lu, Shunan Qi, Bo Chen, Ziyu Li, Shixin Liu, Jun Wang, Wenling Wang…
    Citation: BMC Gastroenterology 2022 22:359
  20. Recent studies have shown that chronic kidney disease (CKD) prevalence is significantly higher in patients with hepatic steatosis (HS); however, it remains unclear whether HS is associated with serum creatinin...

    Authors: Juan Ma, Zhongcao Wei, Qian Wang, Xiaolan Lu, Zhihua Zhou, Ruohan Li, Qiuai Shu, Yixin Liu, Jinhai Wang, Na Liu and Haitao Shi
    Citation: BMC Gastroenterology 2022 22:358
  21. Situs inversus totalis (SIT) is a rare congenital anomaly characterized by a complete transposition of all the viscera. SIT cases were usually reported because of the presence of tumors, leading to false assoc...

    Authors: Cheng Zhang, Bo Zhang, Haifeng Huang, Qida Hu, Yibing Jin, Qingsong Yu, Junsen Wang, Xin Zhang and Yun Zhang
    Citation: BMC Gastroenterology 2022 22:357
  22. Authors: Michael V. Chiorean, Jessica R. Allegretti, Puza P. Sharma, Benjamin Chastek, Leonardo Salese, Elizabeth J. Bell, Jesse Peterson-Brandt, Joseph C. Cappelleri, Xiang Guo and Nabeel Khan
    Citation: BMC Gastroenterology 2022 22:356

    The original article was published in BMC Gastroenterology 2022 22:177

  23. We retrospectively compared the effect of endoscopic variceal obturation (EVO) and retrograde transvenous obliteration (RTO) in acute cardiofundal variceal bleeding.

    Authors: Han Ah Lee, Jungwon Kwak, Sung Bum Cho, Young-Sun Lee, Young Kul Jung, Ji Hoon Kim, Seung Up Kim, Hyonggin An, Hyung Joon Yim, Jong Eun Yeon and Yeon Seok Seo
    Citation: BMC Gastroenterology 2022 22:355
  24. To evaluate the usefulness of Contrast-enhanced ultrasound (CEUS) in the diagnosis and differential diagnosis of Polypoid lesions of gallbladder (PLGs) ≥ 1 cm.

    Authors: Xiaoyue Zhang, Shaoshan Tang, Liping Huang, Hong Jin, Yijiao Wang, Yao Wang, Zhan Liu and Chunyu Lu
    Citation: BMC Gastroenterology 2022 22:354
  25. Upper gastrointestinal bleeding (UGIB) is a common complication in renal transplant recipients. However, the risk stratification value of bleeding scoring systems in these patients is unclear, and data regardi...

    Authors: Rui Wang and Qiang Wang
    Citation: BMC Gastroenterology 2022 22:353
  26. Chronic atrophic gastritis (CAG) is a precancerous disease that often leads to the development of gastric cancer (GC) and is positively correlated with GC morbidity. However, the sensitivity of the endoscopic ...

    Authors: Quchuan Zhao, Qing Jia and Tianyu Chi
    Citation: BMC Gastroenterology 2022 22:352
  27. Liver cancer is a severe public health problem worldwide, and it creates a relatively higher disease burden in China than in the Western world. Despite achieving notable progress in China, potential difference...

    Authors: Qiaoxin Wei, Haiyang Zhou, Xinhui Hou, Xiaoping Liu, Sisi Chen, Xueying Huang, Yu Chen, Mei Liu and Zhongping Duan
    Citation: BMC Gastroenterology 2022 22:351
  28. To identify patients suitable for endoscopic injection sclerotherapy (EIS) by evaluating their portal hemodynamics and liver function.

    Authors: Ryuta Shigefuku, Hideaki Takahashi, Tsunamasa Watanabe, Nobuhiro Hattori, Hiroki Ikeda, Kotaro Matsunaga, Takuya Ehira, Tatsuya Suzuki, Nobuyuki Matsumoto, Chiaki Okuse, Motoh Iwasa, Hayato Nakagawa, Fumio Itoh and Michihiro Suzuki
    Citation: BMC Gastroenterology 2022 22:350
  29. To investigate the effects of a reversed segment of the distal small intestine to improve weight gain in an experimental short bowel syndrome (SBS) model in piglets.

    Authors: Lasse Hartmann Schmidt, Jesper Stensig Aa, Bolette Hartmann, Gunvor Iben Madsen, Niels Qvist and Mark Bremholm Ellebæk
    Citation: BMC Gastroenterology 2022 22:349
  30. Hepatocellular carcinoma (HCC) is a kind of tumor with high invasiveness, and patients with advanced HCC have a higher risk of early death. The aim of the present study was to identify the risk factors of earl...

    Authors: Haidong Zhang, Xuanlong Du, Hui Dong, Wenjing Xu, Pengcheng Zhou, Shiwei Liu, Xin Qing, Yu Zhang, Meng Yang and Yewei Zhang
    Citation: BMC Gastroenterology 2022 22:348
  31. Primary gastric lymphoma (PGL) is the most common extranodal non-Hodgkin lymphoma (NHL). Due to the rarity of the disease, it is important to create a predictive model that provides treatment and prognosis for...

    Authors: Jinru Yang, Tao Liu, Ying Zhu, Fangyuan Zhang, Menglan Zhai, Dejun Zhang, Lei Zhao, Min Jin, Zhenyu Lin, Tao Zhang, Liling Zhang and Dandan Yu
    Citation: BMC Gastroenterology 2022 22:347
  32. Adenosquamous carcinoma (ASC)with concurrent gastric carcinoma with lymphoid stroma (GCLS) are extremely rare tumors. There are only limited cases reported in the literature. Epstein–Barr virus (EBV) infection...

    Authors: Fang Cao, Yan Yan, Dongfeng Niu, Xiaozheng Huang, Ling Jia, Xinting Diao and Zhongwu Li
    Citation: BMC Gastroenterology 2022 22:346
  33. Esophageal cancer (EC), one highly malignant gastrointestinal cancer, is the 6th leading cause of cancer-related deaths worldwide. Necroptosis and long non-coding RNA (lncRNA) play important roles in the occur...

    Authors: Yang Liu, Hongyu Hao, Lin Kang, Guona Zheng, Xiaowan Guo, Bingjie Li, Huanfen Zhao and Han Hao
    Citation: BMC Gastroenterology 2022 22:345
  34. Esophageal carcinoma (ESCA) is a common malignancy with a poor prognosis. Previous research has suggested that necroptosis is involved in anti-tumor immunity and promotes oncogenesis and cancer metastasis, whi...

    Authors: Kai Sun, Juan-juan Hong, Dong-mei Chen, Zhan-xiong Luo and Jing-zhang Li
    Citation: BMC Gastroenterology 2022 22:344
  35. Fecal microbiota transplantation (FMT) is a potential treatment for irritable bowel syndrome (IBS), but its efficacy in Japanese IBS patients is unknown. This study aimed to evaluate the efficacy, side effects...

    Authors: Motonobu Hamazaki, Tsunaki Sawada, Takeshi Yamamura, Keiko Maeda, Yasuyuki Mizutani, Eri Ishikawa, Satoshi Furune, Kenta Yamamoto, Takuya Ishikawa, Naomi Kakushima, Kazuhiro Furukawa, Eizaburo Ohno, Takashi Honda, Hiroki Kawashima, Masatoshi Ishigami, Masanao Nakamura…
    Citation: BMC Gastroenterology 2022 22:342
  36. Clinical evidence of the preventive effectiveness of medium-class topical corticosteroids for capecitabine-induced hand foot syndrome (HFS) is limited. Although the pathogenesis and mechanism of HFS are unclea...

    Authors: Yohei Iimura, Naoki Furukawa, Masaaki Ishibashi, Yuka Ahiko, Taro Tanabe, Susumu Aikou, Dai Shida, Masanori Nojima, Seiichiro Kuroda and Narikazu Boku
    Citation: BMC Gastroenterology 2022 22:341
  37. Optimal management of cirrhosis is complex, and patients often lack knowledge and skills, which can affect self-management. We assessed patient knowledge about cirrhosis and examined whether knowledge was asso...

    Authors: Patricia C. Valery, Christina M. Bernardes, Kelly L. Hayward, Gunter Hartel, Katelin Haynes, Louisa G. Gordon, Katherine A. Stuart, Penny L. Wright, Amy Johnson and Elizabeth E. Powell
    Citation: BMC Gastroenterology 2022 22:340
  38. First Nations Peoples of Australia are disproportionally affected by hepatitis C (HCV) infection. Through a prospective study we evaluated the outcome of direct-acting antiviral (DAA) therapy among First Natio...

    Authors: Paul J. Clark, Patricia C. Valery, James Ward, Simone I. Strasser, Martin Weltman, Alexander Thompson, Miriam T. Levy, Barbara Leggett, Amany Zekry, Julian Rong, Peter Angus, Jacob George, Steven Bollipo, Bruce McGarity, William Sievert, Gerry Macquillan…
    Citation: BMC Gastroenterology 2022 22:339
  39. A missed diagnosis of colorectal polyps during colonoscopy may be associated with the occurrence of interval colorectal cancer. The risk factors for a missed diagnosis or a method to predict the risk of a miss...

    Authors: Xiaobo Wang, Haiyang Guo, Yong Tang, Lin Chen and Xianfei Wang
    Citation: BMC Gastroenterology 2022 22:338
  40. Gastrointestinal bleeding is one of the major gastrointestinal diseases. In this study, our objective was to compare Glasgow-Blatchford score (GBS), AIMS65 score, MAP score, Modified GBS, and Iino score as out...

    Authors: Yoshihiro Sasaki, Tomoko Abe, Norio Kawamura, Taisei Keitoku, Isamu Shibata, Shino Ohno, Keiichi Ono and Makoto Makishima
    Citation: BMC Gastroenterology 2022 22:337
  41. Incidentalomas, defined as incidental findings on imaging, are a growing concern. Our aim was to determine the impact and outcomes of extrahepatic incidentalomas on liver transplantation.

    Authors: Pedro Cortés, Hassan M. Ghoz, Fernando Stancampiano, Mohamed Omer, Balkishan Malviya, Andrew W. Bowman and William C. Palmer
    Citation: BMC Gastroenterology 2022 22:336
  42. Nonalcoholic steatohepatitis (NASH), the inflammatory subtype of nonalcoholic fatty liver disease, is underdiagnosed and expected to become the leading indication for liver transplant in the United States. We ...

    Authors: Mary Rinella, Donna R. Cryer, Amy Articolo, Travis Fisher, Jennifer Schneider and Karl Nadolsky
    Citation: BMC Gastroenterology 2022 22:335
  43. Standard treatment strategy for low rectal cancer in Japan is different from Western countries. Total mesorectum excision (TME) + lateral lymph node dissection (LLND) is mainly carried out in Japan, whereas ne...

    Authors: Hiroshi Miyakita, Lin Fung Chan, Kazutake Okada, Hajime Kayano, Masaki Mori, Sotaro Sadahiro and Seiichiro Yamamoto
    Citation: BMC Gastroenterology 2022 22:334
  44. Hepatic arterial variations were fully elaborated in anatomical monographs. Here, we aimed to present a rare case with multiple arterial variations of the liver complicated laparoscopic pancreaticoduodenectomy.

    Authors: Yong Yan, Bailin Wang, Wei Yuan, Jiansong Zhang, Junhao Xiao and Yanhua Sha
    Citation: BMC Gastroenterology 2022 22:331
  45. Thyroid dysfunction has been reported in severe liver diseases. The aim of this study was to analyze the impact of serum thyroid-stimulation hormone (TSH) levels on the prognosis of patients with hepatitis B v...

    Authors: Jun-feng Chen, Wei-zhen Weng, Miao Huang, Xiao-hua Peng, Jing Zhang, Jing Xiong, Jian-rong He, Shao-quan Zhang, Hui-juan Cao, Bin Gao, Deng-na Lin, Juan Gao, Zhi-liang Gao and Bing-liang Lin
    Citation: BMC Gastroenterology 2022 22:330

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