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  1. Our study aimed to analyze the characteristics of ultrasound images corresponding to each histological stage of primary biliary cholangitis (PBC).

    Authors: Yuan Zhang, Xing Hu, Jing Chang, Weihua Li, Chunyang Huang, Haiping Zhang, Jianjun Shen, Ning Shang and Fankun Meng
    Citation: BMC Gastroenterology 2023 23:448
  2. Proton-pump inhibitors (PPIs) are the most effective drugs for treating acid-related disorders. However, once-daily dosing with conventional PPIs fail to fully control acid secretion over 24 h. This study aime...

    Authors: Hyun Lim, Jong Kyu Park, Hyunsoo Chung, Si Hyung Lee, Jae Myung Park, Jung Ho Park, Gwang Ha Kim, Sung Kwan Shin, Su Jin Hong, Kwang Jae Lee, Moo In Park, Hye-Kyung Jung, Hyun-Soo Kim, Jae Kyu Sung, Seong Woo Jeon, Suck Chei Choi…
    Citation: BMC Gastroenterology 2023 23:447
  3. To explore the underlying causality between leukocyte telomere length (LTL) and four gastrointestinal diseases, we designed a two-sample bidirectional Mendelian randomization study.

    Authors: Haikuo Wang, Xiaolin Chen, Siming Wang and Heyun Zhang
    Citation: BMC Gastroenterology 2023 23:446
  4. The development and implementation of the transition from pediatric to adult healthcare systems for adolescents with inflammatory bowel disease (IBD) should consider stakeholders’ perceptions. This study aimed...

    Authors: Mi Zhou, Youjun Xu and Yunxian Zhou
    Citation: BMC Gastroenterology 2023 23:445
  5. Acute appendicitis (AA) is among the most common nontraumatic indications for emergent abdominal surgical procedures. However, accurately diagnosing all cases can be challenging, physical examination, biochemi...

    Authors: Mohamed Osman Suliman Basher, Ahmed Abdelfattah Ahmed and Aamir Abdullahi Hamza
    Citation: BMC Gastroenterology 2023 23:444
  6. The objectives of this study were to present an accessible C-shaped partial stapled hemorrhoidopexy (C-PSH) in the treatment of grade IV hemorrhoids and to assess long-term outcomes of this technique compared ...

    Authors: Jun He, Meng-Dan Zhou, Wen-Jing Wu, Zhi-Yong Liu, Dong Wang, Guan-Gen Yang, Qin-Yan Yang and Zhong Shen
    Citation: BMC Gastroenterology 2023 23:443
  7. Anal fistula is a common benign anorectal disease that often requires surgical intervention for effective treatment. In recent years, preoperative colonoscopy as a diagnostic tool in patients with anal fistula...

    Authors: Shumin Xu, Luo Zhang, Zhi Li, Kaiping Wang, Fang Liu and Bo Cao
    Citation: BMC Gastroenterology 2023 23:442
  8. Recent studies show the potential role of dietary quality and quantity in predicting the risk of chronic diseases, such as liver disease, therefore, in the present study, we aimed to assess the association of ...

    Authors: Narjes Najibi, Mitra Kazemi Jahromi, Farshad Teymoori, Hossein Farhadnejad, Ammar Salehi-Sahlabadi and Parvin Mirmiran
    Citation: BMC Gastroenterology 2023 23:441
  9. Type 1 gastric neuroendocrine tumors (NETs) are relatively rare to the extent that some physicians have little experience in diagnosing and treating them. The purpose of this study was to increase the understa...

    Authors: Ying-Ying Chen, Wen-Juan Guo, Yan-Fen Shi, Fei Su, Fu-Huan Yu, Ru-Ao Chen, Chao Wang, Ji-Xi Liu, Jie Luo and Huang-Ying Tan
    Citation: BMC Gastroenterology 2023 23:440
  10. Gastroesophageal Reflux Disease (GERD) is a common chronic condition. Its chronic nature may affect the pattern of medication use. This study aimed to investigate the prevalence, associated factors, and patter...

    Authors: Arash Ghamar-Shooshtari, Zahra Rahimian, Hossein Poustchi, Zahra Mohammadi, Bita Mesgarpour, Mohammadreza Akbari, Alireza Kamalipour, Seyed Reza Abdipour-Mehrian, Elham-Sadat Hashemi, Pooria Zare, Kamran Bagheri Lankarani, Reza Malekzadeh, Fatemeh Malekzadeh and Hossein Molavi Vardanjani
    Citation: BMC Gastroenterology 2023 23:439
  11. The introduction of biological drugs has led to great expectations and growing optimism in the possibility that this new therapeutic strategy could favourably change the natural history of Inflammatory Bowel D...

    Authors: M. Valvano, A. Vinci, N. Cesaro, S. Frassino, F. Ingravalle, M. Ameli, A. Viscido, S. Necozione and G. Latella
    Citation: BMC Gastroenterology 2023 23:438
  12. Inflammatory bowel disease (IBD) patients have a higher risk of metabolic dysfunction-associated fatty liver disease (MAFLD) compared with the general population. However, it is not known whether available non...

    Authors: Tiago Lima Capela, Vítor Macedo Silva, Marta Freitas, Cátia Arieira, Tiago Cúrdia Gonçalves, Francisca Dias de Castro, Joana Magalhães and José Cotter
    Citation: BMC Gastroenterology 2023 23:437
  13. Jaundice occurs in some pancreatic disease. However, its occurrences and role in pancreatic neuroendocrine neoplasms (PNENs) has not been well studied. In this study we showed the association between jaundice ...

    Authors: Yongkang Liu, Jiangchuan Wang, Hao Zhou, Zicheng Wei, Jianhua Wang, Zhongqiu Wang and Xiao Chen
    Citation: BMC Gastroenterology 2023 23:436
  14. Colorectal cancer (CRC) screening has been implemented in Tianjin, China since 2012. The objective was to estimate the neoplasia detection rate in a high-risk population by age and sex and to investigate the p...

    Authors: Zhen Yuan, Shuyuan Wang, Yuqi Wang, Hongzhou Li, Weifeng Gao, Xinyu Liu, Youkui Han, Zhaoce Liu, Qinghuai Zhang, Hong Ma, Junying Wang, Xiaomeng Wei, Xipeng Zhang, Wei Cui and Chunze Zhang
    Citation: BMC Gastroenterology 2023 23:435
  15. The incidence of colorectal cancer (CRC) has increased in Iran, and determining the dietary patterns that can contribute to reducing or increasing the risk of CRC will help better control this disease. Therefo...

    Authors: Pegah Hadi Sicahni, Maede Makhtoomi, Kimia Leilami, Zainab Shateri, Farzaneh Mohammadi, Mehran Nouri, Niloofar Omidbeigi, Sanaz Mehrabani and Bahram Rashidkhani
    Citation: BMC Gastroenterology 2023 23:434
  16. Acceptability and tolerance of bowel preparation is critical to overcome patient hesitancy in undergoing colon cancer screening and surveillance colonoscopy. To improve patient experience, a new sports drink-f...

    Authors: Gregory Wiener, Peter Winkle, John D. McGowan, Mark vB. Cleveland and Jack A. Di Palma
    Citation: BMC Gastroenterology 2023 23:433
  17. Stomach adenocarcinoma (STAD) is a significant contributor to cancer-related mortality worldwide. Although previous research has identified endoplasmic reticulum stress (ERS) as a regulator of various tumor-pr...

    Authors: Zhaoxiang Song, Mengge Su, Xiangyu Li, Jinlin Xie, Fei Han and Jianning Yao
    Citation: BMC Gastroenterology 2023 23:432
  18. Antibiotic use in the early stages of acute pancreatitis is controversial. The purpose of this study was to investigate the effect of early antibiotic application on the prognosis of acute pancreatitis (AP).

    Authors: Yi Wen, Lili Xu, Dayi Zhang, Wenwu Sun, Zaiqian Che, Bing Zhao, Ying Chen, Zhitao Yang, Erzhen Chen, Tongtian Ni and Enqiang Mao
    Citation: BMC Gastroenterology 2023 23:431
  19. There is no study evaluating the association between exercise and functional dyspepsia (FD) based on the Rome IV criteria. We aimed to investigate the prevalence of FD and evaluate the association between exer...

    Authors: Zhongcao Wei, Yan Yang, Ting Du, Yujie Hao, Na Liu, Yong Gu and Jinhai Wang
    Citation: BMC Gastroenterology 2023 23:430
  20. Chronic gastritis, especially that caused by helicobacter pylori (HP) infection, has been associated with increased risk of ischemic stroke. But the relationship between chronic gastritis and cerebral small ve...

    Authors: Cunsheng Wei, Chang Tan, Xuemei Zhang, Xin Shen, Zongliang Xu, Junrong Li and Gelin Xu
    Citation: BMC Gastroenterology 2023 23:429
  21. The D2 procedure has been accepted as the standard treatment for advanced gastric cancer (GC) in East Asia. Determination of the number of lymph nodes (LNs) after gastrectomy may influence the pathological sta...

    Authors: Hanting Xiang, Zhebin Dong, Hengmiao Wu, Yicheng He, Zhengwei Chen, Sangsang Chen, Weiming Yu and Chao Liang
    Citation: BMC Gastroenterology 2023 23:428
  22. Whether body mass index (BMI) is a risk factor for poor bowel preparation is controversial, and the optimal bowel preparation regimen for people with a high BMI is unclear.

    Authors: Hailin Yan, Hongyu Huang, Dailan Yang, Zonghua Chen, Chao Liu, Zhong Huang, Rui Zhao, Jing Shan, Li Yang, Jinlin Yang and Kai Deng
    Citation: BMC Gastroenterology 2023 23:427
  23. This study aims to assess the prevalence of Helicobacter pylori (Hp) infection at the household level in Hainan Province in China and identify the factors that contribute to its spread. The findings of this study...

    Authors: Danni Liu, Jing Pan, Zhengyi Chen, Sailian Li, Jiamei Ma, Yening Xiao, Danhong Wang, Ganggang Mu, Ya Lin, Juyuan Li, Zhai Chen and Xiaoxi Huang
    Citation: BMC Gastroenterology 2023 23:426
  24. The effect of Helicobacter pylori (H.pylori) eradication therapy on mixed-histological-type gastric cancer remains unclear. This study aimed to clarify the effect of H. pylori eradication therapy on mixed-histolo...

    Authors: Yoshitaka Tokai, Yusuke Horiuchi, Noriko Yamamoto, Ken Namikawa, Shoichi Yoshimizu, Akiyoshi Ishiyama, Toshiyuki Yoshio, Toshiaki Hirasawa and Junko Fujisaki
    Citation: BMC Gastroenterology 2023 23:425
  25. Intraductal papillary mucinous neoplasm (IPMN) is a cystic tumor of the pancreas arising from abnormal papillary proliferation of ductal epithelial cells, and is a precancerous lesion of pancreatic malignancy....

    Authors: Ji-Hao Xu, Chu-Yan Ni, Yan-Yan Zhuang, Li Li, Ying Lin, Zhong-Sheng Xia, Wei-Rong Wu, Qi-Kui Chen and Wa Zhong
    Citation: BMC Gastroenterology 2023 23:424
  26. The present study aims to explore the clinical application of enhanced recovery after surgery (ERAS) in pediatric patients with congenital upper gastrointestinal obstruction (CUGIO).

    Authors: Li-Bo Zhu, Yang-Fang Li, Jun-Tao Shu, Min Xi, Qiang Bai, Jian-Hong Yan, Ling Liu and Cui-Lian Li
    Citation: BMC Gastroenterology 2023 23:423
  27. The prognosis of patients with extrahepatic cholangiocarcinoma (ECCA) must be determined with precision. However, the usual TNM staging system has the drawback of ignoring age, adjuvant therapy, and gender and...

    Authors: Yu Zhang, Chunzhong Qiao, Peng Zhao and Changhe Zhang
    Citation: BMC Gastroenterology 2023 23:422
  28. Identifying risk factors for metachronous colorectal cancer (CRC) and metachronous advanced neoplasia could be useful for guiding surveillance. We conducted a systematic review and meta-analysis to investigate...

    Authors: Ye Zhang, Amalia Karahalios, Ye Kyaw Aung, Aung Ko Win, Alex Boussioutas and Mark A. Jenkins
    Citation: BMC Gastroenterology 2023 23:421
  29. Single-incision plus one-port laparoscopic surgery (SILS + 1) has been demonstrated to be minimally invasive while possessing better cosmesis and less pain compared with conventional laparoscopic surgery (CLS)...

    Authors: Mingyi Wu, Hao Wang, Xuehua Zhang, Jiaolong Shi, Xiaoliang Lan, Tingyu Mou and Yanan Wang
    Citation: BMC Gastroenterology 2023 23:420
  30. Demonstration of access to the bile duct through Enlarged Papillary Fistulotomy, a method different from conventional fistulotomy.

    Authors: Alexandre Gomes, Ana Sarah Rafka Haidar, Giovani Caetano Padilha, Juliana Bara, Mariana Sussai Nonato, José Mauro da Silva Rodrigues, Pérsio Campos Correia Pinto, Ricardo de Oliveira Ayres and Ronaldo Antonio Borghesi
    Citation: BMC Gastroenterology 2023 23:419
  31. Vedolizumab (VDZ), a gut-selective anti-lymphocyte trafficking integrin antibody, is effective in treating patients with moderately to severely active Crohn’s disease (CD). In this study, we examined the real-...

    Authors: Roni Weisshof, Stephan R. Vavricka, Lieven Pouillon, Fiona Braegger, Montserrat Roset, Nawal Bent-Ennakhil and Marc Ferrante
    Citation: BMC Gastroenterology 2023 23:417
  32. Cancer-associated fibroblasts (CAFs) have been reported to exhibit protumorigenic effects. Among the well-known CAF markers such as smooth muscle actin (SMA) and fibroblast activation protein (FAP), high expre...

    Authors: Yuhei Waki, Yuji Morine, Takayuki Noma, Chie Takasu, Hiroki Teraoku, Shinichiro Yamada, Yu Saito, Tetsuya Ikemoto and Mitsuo Shimada
    Citation: BMC Gastroenterology 2023 23:415
  33. There are different therapeutic approaches for biliary strictures and reducing portal hypertension in patients with symptomatic portal cavernoma cholangiopathy (PCC). Endoscopic treatment includes endoscopic b...

    Authors: Abdullah Murat Buyruk, Çağdaş Erdoğan, Fatih Tekin, İlker Turan, Ömer Özütemiz and Galip Ersöz¹
    Citation: BMC Gastroenterology 2023 23:414
  34. Common variable immunodeficiency disorder (CVID) patients may have gastrointestinal (GI) involvement and suffer from infections, which are poorly understood. This study aimed to evaluate the clinical, endoscop...

    Authors: Yang Chen, Yan You, Ji Li, Aiming Yang, Weixun Zhou and Xiaoqing Li
    Citation: BMC Gastroenterology 2023 23:413

    The Correction to this article has been published in BMC Gastroenterology 2024 24:15

  35. Novel endoscopic techniques used in the treatment of gastric lesions with local submucosal fibrosis need preclinical evaluation and training due to safety limitations. Therefore, the purpose of our study was t...

    Authors: Xiao-Jian He, Xiao-Ling Wang, Chuan-Shen Jiang, Dong-Gui Hong, Hai-Lan Lin, Yun-Ping Zheng, Han Li, Xin-Jiang Chen, Jian-Xiao Huang, Ling-Shuang Dai, Mei-Yan Liu, Bao-Xiang Luo, Dong-Liang Li, Da-Zhou Li and Wen Wang
    Citation: BMC Gastroenterology 2023 23:412
  36. T cell transfer colitis model is often used to study the CD4+ T cell functions in the intestine. However, the specific roles of macrophages in colitis remain unclear. In this study, we aimed to evaluate the pheno...

    Authors: Shin Ebihara, Toshiki Urashima, Wataru Amano, Hideto Yamamura and Noriko Konishi
    Citation: BMC Gastroenterology 2023 23:411
  37. Life-threatening bleeding following endoscopic variceal ligation (EVL) in patients with cirrhosis rarely can occur. The present study aimed to evaluate the performance of computed tomography (CT) in predicting...

    Authors: Hwaseong Ryu, Tae Un Kim, Ki Tae Yoon and Young Mi Hong
    Citation: BMC Gastroenterology 2023 23:410
  38. To present a study to identify the characteristics of coexisting early gastric cancer (EGC) and benign submucosal lesions, with the aim of reducing the adverse consequences of overdiagnosis and overtreatment.

    Authors: Huawei Yang, Zhen Li, Zhi Wei, Guodong Li, Yi Li, Shanbin Wu and Rui Ji
    Citation: BMC Gastroenterology 2023 23:409
  39. Gastrointestinal Neuroendocrine Neoplasms (GI-NENs) often result in liver metastases, and the role of Primary Tumor Resection (PTR) in managing GI-NENs with liver metastases (GI-NENLM) is still debated. This s...

    Authors: Yifan Liu, Zhixiong Wang, Qi Lin, Ruizhe Cui, Wei Tang, Guanghua Li and Zhao Wang
    Citation: BMC Gastroenterology 2023 23:408
  40. Women experience more severe gastrointestinal (GI) symptoms compared to men. The onset of puberty and the menstrual cycle may influence these differences. Additionally, health anxiety is an important construct...

    Authors: Sivanne Mendelson, Preethashree Anbukkarasu, Jeffrey E. Cassisi and Widaad Zaman
    Citation: BMC Gastroenterology 2023 23:406
  41. Many patients with ulcerative colitis (UC) gain weight after treatment. However, the clinical significance of weight gain in these patients remains unclear. This study aimed to evaluate body weight changes aft...

    Authors: Hyuk Yoon, Young Soo Park, Jeong Eun Shin, Byong Duk Ye, Chang Soo Eun, Soon Man Yoon, Jae Myung Cha, You Sun Kim, Kyu Chan Huh, Young Sook Park, Jae Hee Cheon, Eun Suk Jung, Youngdoe Kim and Su Young Jung
    Citation: BMC Gastroenterology 2023 23:405
  42. Very early-onset inflammatory bowel disease (VEOIBD) with interleukin-10 (IL10R) signaling deficiency usually requires enterostomy in patients who are refractory to traditional treatment. This study aimed to e...

    Authors: Zifei Tang, Song Sun, Min Ji, Peng Shi, Yuhuan Wang, Zhiheng Huang and Ying Huang
    Citation: BMC Gastroenterology 2023 23:404
  43. To date, an increasing number of studies have revealed that GP73 may have prognostic value in liver cancer. However, most of the studies evaluated serum GP73, and the results regarding the prognostic value of ...

    Authors: Wei-Ming Yu, Guo-Wei Li, Ming-Geng Lou and Zheng-Yu Wu
    Citation: BMC Gastroenterology 2023 23:401
  44. Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease characterized by inflammation of the interlobular bile ducts. Ursodeoxycholic acid (UDCA) is the only FDA approved first-line therapy fo...

    Authors: Huiling Zhu, Mengyao Zheng, Haiyu He, Hongtao Lei, Wenlin Tai and Jinhui Yang
    Citation: BMC Gastroenterology 2023 23:400
  45. Infiltration of CD8 + T cells in the tumor microenvironment is correlated with better prognosis in various malignancies. Our study aimed to investigate vital genes correlated with CD8 + T cell infiltration in ...

    Authors: Dun Pan, Hui Chen, Jiaxiang Xu, Xin Lin and Liangqing Li
    Citation: BMC Gastroenterology 2023 23:399

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