Liver biopsy | FibroMeter | Fibrotest | Fibroscan | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2G | 3G | |||||||||||||||
Population # | 1 | 1 | 1 | 2 | 3 | 4 | 1 | 2 | 3 | 4 | 1 | 2 | 3 | 4 | 3 | 4 |
Pathologist | Local a | Expert | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Metavir FM staging | 52.2/64.4 | 82.2 | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Binary diagnosis b | 77.1/85.9 | 91.4 | 75.3 | 78.1* | 75.2 | 77.7 | 75.5 | 77.9* | 74.0 | 76.8 | 74.2 | 74.5* | 71.3 | 75.2 | 73.7 | 75.2 |
Fibrosis class classification c | - | - | 76.3 | 74.9* | 68.7 | 68.2 | 89.0 | 86.9* | 77.1 | 83.4 | 34.3 | 37.9* | 42.5 | 33.5 | 64.9 | 50.7 |
Discrepancy score d | 0.55/0.40 | 0.17 | 0.30 | 0.30 | 0.36 | 0.38 | 0.11 | 0.14 | 0.23 | 0.17 | 0.86 | 0.84 | 0.86 | 0.92 | 0.50 | 0.64 |
Significant discrepancy (%) e | 7.3/4.9 | 0.0 | 5.6 | 4.6 | 5.7 | 6.0 | 0.5 | 0.7 | 0.9 | 0.9 | 17.2 | 18.2 | 21.3 | 22.2 | 12.9 | 12.3 |