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Table 3 Univariate and multivariate Cox proportional hazard ratio regression model of mortality risk considering relative age-related confounding factors

From: The Role of Age in Predicting the Outcome of Caustic Ingestion in Adults: A Retrospective Analysis

 

Univariate

Multivariate

Variables

HR

(95% CI for HR)

Pvalue

HR

(95% CI for HR)

Pvalue

Age

      

   < 65 years

(Reference)

  

(Reference)

  

   ≧65 years

5.63

(2.48 - 12.76)

< .001*

1.09

(0.80 - 1.48)

0.585

Gender1

      

   Females

(Reference)

  

(Reference)

  

   Males

1.94

(0.84 - 4.51)

0.122

1.24

(0.98 - 1.57)

0.070

Substance 1

      

   Clean detergent

1.79

(0.43 - 7.49)

0.428

-

  

   HCl

2.72

(0.79 - 9.38)

0.114

-

  

   Other

(Reference)

  

-

  

Acid/alkaline1

      

   Acid

(Reference)

  

-

  

   Alkaline

1.36

(0.57 - 3.24)

0.485

-

  

   Unknown

1.84

(0.47 - 8.23)

0.426

-

  

Grade 1

      

   1

0

(0 - 7.75 × 10302)

0.970

1.90

(1.29 - 2.80)

0.001*

   2a/2b

0.19

(0.06 - 0.57)

0.003*

0.88

(0.64 - 1.20)

0.404

   3a

0.12

(0.02 - 0.87)

0.037*

1.18

(0.82 - 1.70)

0.366

   3b

(Reference)

  

(Reference)

  

Most severe site of damage observed by endoscopy 1

      

   Esophagus

(Reference)

  

-

  

   Stomach

1.00

(0.33 - 3.08)

0.994

-

  

   Duodenum

2.92

(0.78 - 10.86)

0.111

-

  

Furthest location reached by endoscope 1

      

   Esophagus

(Reference)

  

(Reference)

  

   Stomach

0.14

(0.03 - 0.73)

0.019*

0.90

(0.33 - 2.49)

0.839

   Duodenum

0.06

(0.16 - 0.22)

< .001*

0.64

(0.25 - 1.59)

0.334

Suicide/Accident 1

      

   Suicide

4.34

(1.02 - 18.50)

0.047*

1.19

(0.92 - 1.54)

0.187

   Accident

(Reference)

  

(Reference)

  

Systemic complications 1

26.44

(7.69 - 90.90)

< .001*

-

  

   Aspiration pneumonia1

1.15

(0.82 - 1.63)

0.423

0.93

(0.59 - 1.47)

0.750

   Respiratory failure1

2.14

(1.35 - 3.39)

0.001

1.78

(0.99 - 3.22)

0.055

   DIC1

1.38

(0.62 - 3.11)

0.434

1.18

(0.48 - 2.90)

0.724

   Hepatic1

2.37

(1.29 - 4.36)

0.006

2.69

(1.41 - 5.13)

0.003*

   GI complications1

2.85

(1.26 - 6.48)

0.012*

0.76

(0.54 - 1.05)

0.094

   Fever1

7.36

(2.96 - 18.25)

< .001*

0.63

(0.39 - 1.03)

0.063

   Antibiotic usage1

14.12

(4.13 - 48.19)

< .001*

1.87

(1.18 - 2.97)

0.008*

   Psychological comorbidity1

1.43

(0.63 - 3.29)

0.395

-

  

   Systemic comorbidiy1

1.54

(0.60 - 3.97)

0.375

-

  
  1. 1The age classification was adjusted to avoid selection bias due to age.
  2. * P value < 0.05
  3. DIC, disseminated intravascular coagulation
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BMC Gastroenterology

ISSN: 1471-230X

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