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Table 2 The diagnostic performance of liver SWV and FibroTest in classifying METAVIR fibrosis (F) stages

From: Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C

 

METAVIR

F1vsF2-4

F1-2vsF3-4

F1-3vsF4

 

Liver SWV

AUC (95% CI)

0.847(0.779-0.914)

0.902 (0.835-0.970)

0.831 (0.723-0.939)

SE of AUC

0.034

0.035

0.055

Cutoff (m/s)

1.55

1.81

1.98

Sensitivity

74.1%

90.2%

88.9%

Specificity

87.0%

89.5%

79.8%

PPV

90.9%

80.4%

42.1%

NPV

65.6%

95.0%

97.8%

Concordance

78.8%

89.7%

81.1%

Discordance

21.2%

10.3%

18.9%

+LR

5.7

8.6

4.4

-LR

0.3

0.1

0.1

DOR(95% CI)

19.0(7.1-51.3)

79.1(22.9-273.8)

31.6(6.8-147.9)

 

FibroTest

AUC (95% CI)

0.823(0.748-0.898)

0.812 (0.735-0.888)

0.757 (0.648-0.865)

SE of AUC

0.038

0.039

0.055

  1. Concordance = (true positive n + true negative n)/127, and discordance = (false positive n + false negative n)/127; AUC, area under the receiver operating characteristic curve; DOR, diagnostic odds ratio; LR, likelihood ratio; NPV, negative predictive value; PPV, positive predictive value; SE, standard error; SWV, shear wave velocity.
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BMC Gastroenterology

ISSN: 1471-230X

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