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Table 1 Base-line characteristics of controls and patients before antiviral treatment

From: Study of the effect of antiviral therapy on homocysteinemia in hepatitis C virus- infected patients

Laboratory parameters

Reference values

Control Group (n = 70)

Patients Group (n = 532)

P

Hb (g/dl)

M:13.5-18.0; F:11.5-16.5

14.19 ± 1.65

13.01 ± 1.98

<0.0001***

PLT (*100)

150-450*100

276.64 ± 75.31

545.79 ± 85.38

<0.0001***

TLC

4000-11000

6.14 ± 1.53

5.62 ± 2.36

=0.01*

ESR (mm/hr)

M:0–10; F:0-15

13.18 ± 1.47

37.63 ± 22.34

<0.0001***

ALT (U/L)

M:0–40; F:0-37

33.2 ± 7.45

110.47 ± 128.85

<0.0001***

ALP (U/L)

60-306

214.61 ± 64.23

259.64 ± 64.07

<0.0001***

Cholesterol (mmol/L)

Normal: 3.4-5.2; Borderline high: 5.2-6.2; High: >6.22

4.67 ± 0.36

5.6 ± 0.76

<0.0001***

HDL (mmol/L)

0.8-1.7

1.11 ± 0.16

1.30 ± 0.44

<0.0001***

LDL (mmol/L)

<3.8

2.92 ± 0.29

3.27 ± 0.72

<0.0001***

TGs (mmol/L)

0.4-1.9

1.31 ± 0.49

2.10 ± 0.70

<0.0001***

Hcy (μmol/L)

5-15

12.36 ± 1.64

25.66 ± 8.89

<0.0001***

  1. ***: extremely statistically significant; **: very statistically significant; *: statistically significant; +: statistically non-significant. Hb: hemoglobin; PLT: platelets; TLC: total leukocyte count; ESR: erythrocyte sedimentation rate; ALT: alanine amino transferase; ALP: alkaline phosphatase; HDL: high density lipids; LDL: low density lipids; TGs: triglycerides; Hcy: homocysteine.