Figure 1
From: High glucose increases LPS-induced DC apoptosis through modulation of ERK1/2, AKT and Bax/Bcl-2
The effects of high glucose on LPS-induced dendritic cell apoptosis in mouse intestinal tract in vivo . (A) A representative FACS plot of intestinal DC apoptosis at 24 h. The upper left quadrant represents the apoptotic cells (Annexin-V+ (An+) PI-); the lower left is live cells (An- PI-); the upper right is dead cells (An+ PI+). (B) Summary of intestinal DC apoptosis from mice administrated LPS 24 h previously. STZ treated mouse were used as the high glucose group. High glucose significantly increased apoptosis of intestinal DC, #p < 0.05 vs. control mice.