Table 5 Sensitivity, specificity and predictive values of NashTest for the diagnosis of NASH
NashTest diagnosis | Histological Diagnosis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Training Group n = 160 | Validation Group n = 97 | All patients n = 257 | ||||||||||
Se | Sp | PPV | NPV | Sensitivity | Specificity | PPV | NPV | Sensitivity | Specificity | PPV | NPV | |
NASH | 11/28 39% | 122/132 92% | 11/21 52% Prevalence = 0.18 | 122/139 88% | 10/35 29% | 61/62 98% | 10/11 91% Prevalence = 0.36 | 61/86 71% | 21/63 33% | 183/194 94% | 21/32 66% Prevalence = 0.25 | 183/225 81% |
Borderline or NASH | 96/103 93% | 20/57 35% | 96/133 72% Prevalence = 0.64 | 20/27 74% | 44/56 79% | 29/41 71% | 44/56 79% Prevalence = 0.58 | 29/41 71% | 140/159 88% | 49/58 50% | 140/189 74% Prevalence = 0.62 | 49/68 72% |