| Index Study (n = 46 records) | 3rd Study (n = 156 records) | ||
---|---|---|---|---|
Period | Integrated Acid (mmol.hr/L) | Time pH < 4 (%) | Integrated Acid (mmol.hr/L) | Time pH < 4 (%) |
24-hour (900–900) |  |  |  |  |
ROC Area | 0.77 (0.59, 0.94) | 0.68 (0.52, 0.83) | 0.74 (0.66, 0.82) | 0.64 (0.55, 0.74) |
Overall Odds Pathologic Reflux | 0.18 | 0.77 | 0.37 | 2.52 |
Postprandial (900–2200) |  |  |  |  |
ROC Area | 0.71 (0.55, 0.88) | 0.69 (0.52, 0.85) | 0.80 (0.74, 0.87) | 0.77 (0.70, 0.85) |
Overall Odds Pathologic Reflux | 0.44 | 0.48 | 1.05 | 1.31 |
Nocturnal (2200–900) |  |  |  |  |
ROC Area | 0.75 (0.57, 0.93) | 0.62 (0.45, 0.78) | 0.75 (0.67, 0.83) | 0.62 (0.53, 0.71) |
Overall Odds Pathologic Reflux | 0.18 | 0.84 | 0.21 | 1.59 |