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Table 3 Hazard ratios for prevalence of cfPWV, Mets and its components with an elevation in serum ALT levels

From: The relationship of serum alanine aminotransferase normal-range levels to arterial stiffness and metabolic syndrome in non-drinkers and drinkers: a Chinese community-based analysis

Serum ALT levels

Non-drinkers

Drinkers

HR (95% CI)

P-value

HR (95% CI)

P-value

Mets

≤10 U/L

1

 

1

 

11-20 U/L

3.443(2.160-5.487)

<0.001

4.515(1.373-14.851)

<0.001

21-30 U/L

6.312(3.859-10.324)

<0.001

7.500(2.249-25.011)

<0.001

31-40 U/L

7.786(4.331-13.996)

<0.001

14.318(4.125-49.699)

<0.001

Central obesity

≤10 U/L

1

 

1

 

11-20 U/L

3.300(2.377-4.579)

<0.001

2.789(1.548-5.026)

0.001

21-30 U/L

5.294(3.623-7.734)

<0.001

4.926(2.610-9.296)

<0.001

31-40 U/L

6.202(3.649-10.539)

<0.001

6.778(3.165-14.512)

<0.001

High TG

≤10 U/L

1

 

1

 

11-20 U/L

3.493(2.228-5.475)

<0.001

4.950(1.746-14.035)

0.003

21-30 U/L

5.721(3.550-9.220)

<0.001

12.560(4.369-36.107)

<0.001

31-40 U/L

7.621(4.292-13.532)

<0.001

17.537(5.782-53.191)

<0.001

Low HDL-c

≤10 U/L

1

 

1

 

11-20 U/L

1.152(0.808-1.643)

0.435

7.700(1.040-57.029)

0.046

21-30 U/L

1.415(0.953-2.101)

0.085

12.895(1.726-96.357)

0.013

31-40 U/L

1.631(0.973-2.735)

0.063

16.525(2.136-127.859)

0.007

High blood pressure

≤10 U/L

1

 

1

 

11-20 U/L

2.355(1.688-3.285)

<0.001

1.710(0.914-3.199)

0.093

21-30 U/L

2.969(1.815-4.858)

<0.001

1.960(1.016-3.783)

0.045

31-40 U/L

3.955(2.716-5.758)

<0.001

2.227(1.065-4.659)

0.033

High blood glucose

≤10 U/L

1

 

1

 

11-20 U/L

2.524(1.564-4.075)

<0.001

1.284(0.484-3.403)

0.615

21-30 U/L

2.841(1.699-4.753)

<0.001

1.605(0.585-4.405)

0.358

31-40 U/L

3.296(1.768-6.145)

<0.001

2.852(0.985-8.256)

0.053

cfPWV > 10 m/s

≤10 U/L

1

 

1

 

11-20 U/L

2.481(1.795-3.429)

<0.001

1.437(0.808-2.558)

0.217

21-30 U/L

3.405(2.358-4.918)

<0.001

0.980(0.530-1.812)

0.948

31-40 U/L

2.279(1.403-3.701)

0.001

1.364(0.679-2.740)

0.384

  1. Abbreviations: cfPWV carotid-femoral pulse wave velocity, Mets metabolic syndrome, ALT alanine aminotransferase, HR hazard ratio, CI confidential interval, TG triglyceride, HDL-c high-density lipoprotein-cholesterol