Table 3 Predicting atrophy based on serum PGI levels and PGR
| Â | Cut-off value | Sensitivity (95%CI),% | Specificity (95%CI),% | PPV,% | NPV,% | AUC (95%CI) | Accuracy,% | p |
|---|---|---|---|---|---|---|---|---|
Mild-moderate atrophy | PGI ≤ 50.3 ng/ml | 63.9 (55.5–71.7) | 49.1 (45.7–52.5) | 10.9 | 82.5 | 0.575 (0.544–0.606) | 49.0 | 0.0022 |
PGR ≤ 5.15 | 41.7 (33.5–50.2) | 74.5 (71.5–77.4) | 21.7 | 88.3 | 0.556 (0.524–0.587) | 69.8 | 0.0516 | |
Hp negative | Â | Â | Â | Â | Â | Â | Â | |
PGI ≤ 41.2 ng/ml | 77.6 (65.8–86.9) | 35.4 (31.3–39.6) | 7.4 | 86.8 | 0.568 (0.527–0.608) | 59.9 | 0.0584 | |
PGR ≤ 9.08 | 29.9 (19.3–42.3) | 82.9 (79.4–86.0) | 9.7 | 82.0 | 0.513 (0.472–0.553) | 23.1 | 0.7570 | |
Hp positive | Â | Â | Â | Â | Â | Â | Â | |
PGI ≤ 43.4 ng/ml | 89.6 (80.6–95.4) | 18.1 (14.0–22.7) | 12.1 | 79.2 | 0.521 (0.471–0.571) | 68.1 | 0.5545 | |
PGR ≤ 4.29 | 49.4 (37.8–61.0) | 65.1 (59.6–70.3) | 25.3 | 84.3 | 0.544 (0.493–0.593) | 62.1 | 0.2629 | |
Severe atrophy | PGI ≤ 53.6 ng/ml | 76.9 (46.2–95.0) | 47.0 (43.8–50.2) | 1.9 | 97.3 | 0.575 (0.544–0.606) | 47.4 | 0.3774 |
PGR ≤ 4.28 | 76.9 (46.2–95.0) | 83.4 (80.9–85.7) | 5.8 | 99.6 | 0.818 (0.793–0.842) | 83.3 | <0.0001 | |
Hp negative | Â | Â | Â | Â | Â | Â | Â | |
PGI ≤ 53.6 ng/ml | 100.0 (59.0–100.0) | 33.7% (29.9–37.6) | 1.8 | 100.0 | 0.635 (0.595–0.673) | 34.4 | 0.1696 | |
PGR ≤ 6.28 | 85.7 (42.1–99.6) | 73.9 (70.2–77.4) | 37.5 | 99.8 | 0.833 (0.801–0.862) | 75.0 | 0.0001 | |
Hp positive | Â | Â | Â | Â | Â | Â | Â | |
PGI ≤ 102.9 ng/ml | 66.7 (22.3–95.7) | 9.7 (7.0–13.1) | 1.0 | 94.9 | 0.522 (0.472–0.572) | 10.5 | 0.8856 | |
PGR ≤ 4.28 | 100.0 (54.1–100.0) | 64.3 (59.3–69.0) | 4.1 | 100.0 | 0.789 (0.746–0.828) | 63.3 | <0.0001 |