Table 2 The diagnostic accuracy of biomarkers for early detection of HCC
From: VWF/ADAMTS13 ratio as a potential biomarker for early detection of hepatocellular carcinoma
Variable | OR (95% CI) | P value |
|---|---|---|
Unvariable analysis | ||
 AFP > 10 ng/mL | 1.01 (0.98–1.05) | 0.49 |
 DCP > 40mAU/mL | 5.48 (1.10–27.3) | 0.038 |
 AFP-L3% > 5% | 15.9 (1.89–134.0) | 0.011 |
 VEGF > 100 pg/mL | 7.06 (1.39–35.9) | 0.019 |
 VEGFR2 > 6500 pg/mL | 2.46 (0.796–7.63) | 0.12 |
 ADAMTS13:AC > 60% | 0.31 (0.0874–1.10) | 0.082 |
 VWF:Ag > 300% | 4.31 (1.30–14.3) | 0.017 |
 VWF:Ag/ADAMTS13:AC > 5 | 8.95 (1.82–44.0) | 0.007 |
Multivariable analysis | ||
 AFP-L3% > 5% | 19.5 (1.78–214.0) | 0.015 |
 VWF:Ag/ADAMTS13:AC > 5 | 18.5 (1.64–209.0) | 0.018 |