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Table 3 Comparison of clinical features, endoscopic findings and tissues eosinophilia between the eosinophilic gastroenteritis (EoGE) ulcer and the non-EoGE ulcer group

From: Eosinophilic gastroenteritis as a cause of non-Helicobacter pylori, non-gastrotoxic drug ulcers in children

Variable

Non-EoGE

(N = 236)

EoGE

(N = 19)

P value*

Clinical features

 Male gender (%)

142 (60.2)

15 (78.9)

0.105

 Age, years

10.2 (1–18 days)

13.6 (5.4–17.4)

0.022

 Complications

18 (7.6)

3 (15.8)

0.197

 Bleeding

13 (5.5)

2 (10.5)

0.309

 Obstruction

3 (1.3)

1 (5.3)

0.268

 Perforation

2 (0.8)

0

1.000

 Ulcer recurrence

11 (4.7)

4 (21.1)

0.018

Allergic history

 Atopic dermatitis

5 (2.1)

5 (26.3)

< 0.001

 Allergic rhinitis

10 (7.2)

2 (14.3)

0.305

 Asthma

3 (2.2)

0

1.000

Endoscopic findings n, (%)

 Gastric ulcer only

67 (28.4)

2 (10.5)

0.092

 Duodenal ulcer only

144 (61.0)

15 (78.9)

0.121

 Gastric and Duodenal ulcer

25 (10.5)

2 (10.5)

1.000

 Multiple ulcers

69 (29.2)

4 (21.1)

0.448

 Stomach nodularity

36 (15.3)

5 (26.3)

0.202

 Duodenal nodularity

10 (4.2)

0

1.000

Tissue eosinophils (count/HPF) n, (range)

 Upper esophagus

0 (0–4)

0 (0–103)

< 0.001

 Lower esophagus

0 (0–24)

0 (0–100)

< 0.001

 Stomach, antrum

0 (0–20)

5 (0–168)

< 0.001

 Stomach, body

0 (0–20)

1 (0–55)

< 0.001

 Duodenal bulb

0 (0–18)

35 (0–84)

< 0.001

 Duodenal 2nd portion

0 (0–42)

25 (0–100)

< 0.001

  1. Data are expressed as Data are expressed as number (%) for categorical variables or median (range) for continuous variables
  2. EoGE eosinophilic gastroenteritis, HPF high power field
  3. *P value less than 0.05 was set to be statistically significant