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Fig. 1 | BMC Gastroenterology

Fig. 1

From: Genotype–phenotype associations of polymorphisms within the gene locus of NOD-like receptor pyrin domain containing 3 in Swiss inflammatory bowel disease patients

Fig. 1

Effect of the major alleles of rs10733113, rs4353135 and rs55646866 on clinical parameters in CD patients. The graphs show median Log (max. CDAI) values for maximal CDAI within the 25% and 75% percentile (box borders) and outliers (dots) in CD patients A homozygous for the major allele, heterozygous or homozygous for the minor allele for rs10733113, rs4353135 and rs55646866, B depending on the cumulative genetic risk score for carrying the major allele for rs1073313, rs4353135 and rs55646866. In a linear regression model, a significant negative correlation between the cumulative genetic score and log (max. CDAI) can be observed (Coefficient − 0.097; 95% CI − 0.182 to − 0.011; p = 0.026) C CD duration in months within the 25% and 75% percentile (box borders) and outliers (dots) and D percentage of patients with stenosis that required an operation for treatment of stenosis in CD patients homozygous for the major allele, heterozygous or homozygous for the minor allele for rs10733113, rs4353135 and rs55646866

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BMC Gastroenterology

ISSN: 1471-230X

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