Fig. 6
From: CircRNA circ-ATAD1 suppresses miR-618 maturation to participate in colorectal cancer
Circ-ATAD1 is localized to both nucleus and cytoplasm and directly interacts with premature miR-618. The potential base-pairing formed by circ-ATAD1 and premature miR-618 was predicted by IntaRNA 2.0 (a). Nuclear fractionation assay was used to determine circ-ATAD1 expression in both nuclear (N) and cytosol (C) fractions of WiDr and HT-29 cells (a). RNA pull-down assay was performed to analyze the direct interaction between circ-ATAD1 and premature miR-618 (b). ***p < 0.001