Table 3 Ambulatory pH reflux monitoring results of patients undergoing HREMI and MII-pH or Bravo testing, and stratified by presence or absence of reflux on high resolution esophageal manometry with impedance testing (all patients, and patients on and off PPI)
From: Characterizing reflux on high resolution esophageal manometry with impedance
Ambulatory esophageal reflux monitoring | All patients (n = 229) | Patients with reflux on HREMI (n = 47) | Patients without reflux on HREMI (n = 182) | p value |
|---|---|---|---|---|
Esophageal AET | 9.9 ± 0.9% | 11.6 ± 1.8% | 9.4 ± 1.0% | 0.074 |
Reflux episodes on MII-pH | 46.7 ± 2.3 | 63.5 ± 7.1 | 42.1 ± 2.3 | 0.006 |
Lyon classification | ||||
GERD | 113 (49.3%) | 28 (59.6%) | 85 (46.7%) | 0.014 |
Borderline | 42 (18.3%) | 12 (25.5%) | 30 (16.5%) | |
Normal | 74 (32.3%) | 7 (14.9%) | 67 (26.8%) | |
Patients on PPI (n = 141) | Patients with reflux on HREMI (n = 32) | Patients without reflux on HREMI (n = 109) | p value | |
|---|---|---|---|---|
Esophageal AET | 10.1 ± 1.1% | 10.9 ± 2.2% | 9.8 ± 1.3% | 0.298 |
Reflux episodes on MII-pH | 48.0 ± 3.3 | 61.8 ± 9.5 | 44.0 ± 3.1 | 0.190 |
Lyon classification | ||||
-GERD (AET) | 71 (50.4%) | 18 (56.3%) | 53 (48.6%) | 0.135 |
-Borderline | 29 (20.6%) | 9 (28.1%) | 20 (18.3%) | |
-Normal | 41 (29.1%) | 5 (15.6%) | 36 (33%) | |
Patients off PPI (n = 88) | Patients with reflux on HREMI (n = 15) | Patients without reflux on HREMI (n = 73) | p value | |
|---|---|---|---|---|
Esophageal AET | 9.5 ± 1.3% | 13.1 ± 3.4% | 8.8 ± 1.4% | 0.126 |
Reflux episodes on MII-pH | 44.3 ± 3.5 | 67.1 ± 9.8 | 38.8 ± 3.4 | 0.007 |
Lyon classification | ||||
GERD | 42 (47.7%) | 10 (66.7%) | 32 (42.5%) | 0.105 |
Borderline | 13 (14.8%) | 3 (20%) | 10 (13.7%) | |
Normal | 33 (37.5%) | 2 (13.3%) | 31 (42.5%) | |