Table 1 Clinical and physical characteristics of all patients and according to sarcopenic status
Total (n = 50) | Without sarcopenia (n = 20) | With sarcopenia (n = 30) | p-value* | |
|---|---|---|---|---|
Age (year) (median, IQR) | 63 (54.5, 64.5) | 58 (51, 64) | 63 (58.2, 66.5) | 0.058 |
Gender (female) (%) | 22 (44) | 3 (15) | 19 (63.3) | 0.002 |
BMI (kg/m2) (mean ± SD) | 25.1 (4.5) | 27.4 (4.8) | 23.7 (4.2) | 0.006 |
Etiology of cirrhosis | ||||
Alcohol | 7 (14) | 3 (15) | 4 (13.3) | 0.451 |
Viral hepatitis B | 17 (34) | 10 (50) | 7 (23.3) | |
Viral hepatitis C | 8 (16) | 3 (15) | 5 (16.7) | |
NAFLD | 5 (10) | 1 (5) | 4 (13.3) | |
AILD | 2 (4) | 0 (0) | 2 (6.7) | |
Other | 3 (6) | 0 (0) | 3 (10) | |
> 1 etiology | 8 (16) | 3 (15) | 5 (16.7) | |
Diuretic use (%) | 6 (12) | 1 (5) | 5 (16.7) | 0.381 |
History of HCC | 11 (22) | 6 (30) | 5 (16.7) | 0.311 |
Laboratory variables | ||||
TB (mg/dl), (median, IQR) | 1 (0.5, 1.6) | 0.9 (0.5, 1.4) | 1 (0.7, 2) | 0.321 |
AST (IU/ml), (median, IQR) | 42 (30.5, 68.5) | 35 (25.5, 52.5) | 53 (35.2, 70.5) | 0.07 |
ALT (IU/ml), (median, IQR) | 37 (24.2, 40.8) | 36 (24.2, 39) | 37 (24.2, 43.2) | 0.482 |
ALB (g/dl), (mean ± SD) | 3.9 (0.7) | 4.2 (0.6) | 3.6 (0.6) | 0.002 |
Hb (g/dl), (mean ± SD) | 12.6 (2.5) | 13.8 (2.3) | 11.7 (2.2) | 0.003 |
Platelet (109/l), (mean ± SD) | 131.9 (67.4) | 158.7 (64.7) | 114.1 (64.2) | 0.021 |
INR (median, IQR) | 1.2 (1, 1.3) | 1.1 (1, 1.2) | 1.2 (1.1, 1.4) | 0.068 |
Creatinine (mg/dl), (mean ± SD) | 0.8 (0.2) | 0.9 (0.2) | 0.8 (0.2) | 0.015 |
Child–Pugh score, (median, IQR) | 5 (5, 6) | 5 (5, 5) | 6 (5, 6) | 0.011 |
Child–Pugh | ||||
A/B/C | 41 /6 /2 | 18/2/0 | 23/5/2 | 0.505 |
MELD score, (median, IQR) | 9 (7,11.8) | 8 (6, 10) | 9 (7, 12.8) | 0.208 |
Mean HGS, (median, IQR) | 21.7 (16.5,30.1) | 31.3 (28.6, 34.2) | 16.7 (15, 18.4) | < 0.001 |
SMI (cm2/m2), (mean ± SD) | 37.5 (8.8) | 45.3 (6.7) | 32.3 (5.6) | < 0.001 |