Long-term prognosis of patients with hepatitis B virus–related acute-on-chronic liver failure: a retrospective study

Table 3 Risk factors for 90-day mortality in HBV-ACLF patients

	Univariate analysis	P value	Multivariate analysis	P value
	COR (95% CI)	P value	AOR (95% CI)	P value
Age	1.060 (1.047, 1.074)	< 0.001	1.049 (1.035, 1.063)	< 0.001
Cirrhosis	2.190 (1.694, 2.839)	< 0.001	1.906 (1.448, 2.509)	< 0.001
HE	5.061 (3.718, 6.934)	< 0.001	3.545 (2.520, 4.986)	< 0.001
NA withdrawal	1.665 (1.165, 2.374)	0.005	1.845 (1.267, 2.686)	0.002
HBV + ALD	0.484 (0.245, 0.956)	0.037
AST	1.000 (1.000, 1.000)	0.002
CHE	1.076 (1.059, 1.094)	< 0.001
TBIL	1.003 (1.003, 1.004)	0.001	1.003 (1.002, 1.004)	< 0.001
PT	1.486 (1.317, 1.684)	< 0.001	1.054 (1.037, 1.072)	< 0.001
Cr	0.978 (0.973, 0.982)	< 0.001
FBG	0.924 (0.898, 0.950)	< 0.001
PLT	0.998 (0.997, 0.998)	< 0.001
lgHBV DNA	1.186 (1.155, 1.220)	< 0.001
MELD score	1.155 (1.127, 1.183)	< 0.001
ALSS	0.868 (0.766, 0.977)	0.022

HE hepatic encephalopathy, NA nucleos(t)ide analog, ALD alcoholic liver disease, AST aspartate aminotransferase, CHE cholinesterase, TBIL total bilirubin, PT prothrombin time, Cr creatinine, PLT platelets, FBG fasting blood glucose, MELD model for end-stage liver disease, ALSS artificial liver support system, AOR adjusted odds ratio, COR crude odds ratio

ISSN: 1471-230X