Table 4 Sensitivity and specificity of the stool DNA test targeting methylated SDC2
SDC2-Combine A&B | SDC2-A | SDC2-B | P value | |
|---|---|---|---|---|
Sensitivity (95% CI) | Sensitivity (95% CI) | Sensitivity (95% CI) | ||
CRC | 87.25% (79.27–92.53%) | 85.29% (77.03–91.00%) | 83.33% (74.82–89.42%) | 0.732 |
Advanced adenomas | 52.00% (38.51–65.20%) | 48.00% (34.80–61.49%) | 52.00% (38.51–65.20%) | 0.899 |
SDC2-Combine A&B | SDC2-A | SDC2-B | ||
|---|---|---|---|---|
Specificity (95% CI) | Specificity (95% CI) | Specificity (95% CI) | ||
Normal control | 94.62% (89.11–97.56%) | 96.15% (91.08–98.58%) | 97.69% (93.14–99.51%) | 0.435 |
Colitis | 94.44% (72.35–99.99%) | 94.44% (72.35–99.99%) | 100.00% (79.33–100%) | 0.595 |
Non‐advanced adenoma | 89.74% (75.85–96.51%) | 92.31% (78.97–98.06%) | 94.87% (82.21–99.48%) | 0.697 |