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Table 2 Univariate and multivariate analyses for overall survival in stage I colorectal cancer

From: Survival after curative resection for stage I colorectal mucinous adenocarcinoma

Variable

Univariate analysis

Multivariate analysis

 

Mean OS (95% CI)

p value

HR (95% CI)

p value

Gender

    

 Male

1

0.604

  

 Female

0.861 (0.489–1.517)

   

Age

    

 ≤ 65

1

0.012*

2.217 (1.207–3.751)

0.009*

 > 65

2.030 (1.157–3.563)

   

Preoperative CEA

    

 ≤ 5

1

0.250

  

 > 5

1.596 (0.715–3.566)

   

T classification

    

 T 1

1

0.165

  

 T 2

1.606 (0.818–3.152)

   

Lesion location

    

 Colon

1

0.021*

3.213 (1.355–7.618)

0.008*

 Rectal

2.628 (1.118–6.180)

   

Size

    

 < 3 cm

1

0.884

  

 ≥ 3 cm

0.959 (0.544–1.689)

   

Mucinous histology

    

 MAC

1

0.479

  

 Non-MAC

1.444 (0.519–4.016)

   

LVI

    

 (−)

1

< 0.001*

6.283 (2.749–14.357)

< 0.001*

 (+)

4.666 (2.080–10.465)

   

Less than 12 lymph nodes

    

 Yes

1

0.935

  

 No

1.031 (0.499–2.130)

   

dMMR

    

 Positive

1

0.042*

2.618 (1.025–6.685)

0.044*

 Negative

0.395 (0.156–0.998)

   
  1. The bold and *  indicates p < 0.05
  2. MAC mucinous adenocarcinomas, CEA carcinoembryonic antigen, dMMR deficient mismatch repair
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BMC Gastroenterology

ISSN: 1471-230X

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