Table 1 Patient characteristics

Age at transplant (years, mean [range])

44 [20, 64]

45 [27, 65]

47 [26, 65]

54 [25, 65]

Caucasian race (%)

3 (100)

3 (100)

3 (75)

7 (78)

Male sex (%)

1 (33)

2 (67)

3 (75)

4 (44)

Primary liver diagnosis (%)

 Hepatitis C (non-viremic)

0 (0)

0 (0)

0 (0)

1 (11)

 Alcohol

1 (33)

0 (0)

1 (25)

0 (0)

 Non-alcoholic fatty liver or cryptogenic

1 (33)

0 (0)

1 (25)

3 (33)

 Immune-mediated (PSC, AIH, PBC)

0 (0)

3 (100)

2 (50)

4 (44)

 Other

1 (33)

0 (0)

0 (0)

1 (11)

Months from LT (mean, [range])

8.0 [4.6, 10.2]

44 [0.8, 71.5]

82 [6.5, 119.1]

63 [4.7, 142.5]

Immunosuppression (%)

 CNI therapy

3 (100)

3 (100)

4 (100)

9 (100)

 Mycophenolic acid therapy

3 (100)

3 (100)

2 (50)

2 (22)

 Predisone

1 (33)

3 (100)

1 (25)

4 (44)

Laboratory values (mean, [range])

 ALT (U/L)

172 [68, 252]

165 [27, 302]

54 [20, 84]

98 [22, 303]

 AST (U/L)

115 [27, 178]

104 [50, 134]

41 [18, 64]

44 [22, 103]

 Alkaline phosphatase (U/L)

146 [54, 226]

264 [164, 366]

100 [68, 130]

363 [191, 621]

 Total bilirubin (mg/dL)

1 [0.5, 1.2]

8 [3.5, 12.2]

1 [0.5, 1.5]

1 [0.3, 1.5]

Rejection characteristics (%)

 Mild (RAI 3–4)

1 (33)

–

–

–

 Moderate–Severe (RAI 5–9)

2 (67)

–

–

–

Steatosis characteristics (%)

 None

3 (100)

3 (100)

3 (75)

6 (67)

 Mild

0 (0)

0 (0)

1 (25)

2 (22)

 Moderate

0 (0)

0 (0)

0 (0)

1 (11)

 Severe

0 (0)

0 (0)

0 (0)

0 (0)