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Table 1 The clinical characteristics of the 359 subjects who were screened

From: Feasibility of quantification based on novel evaluation with stool DNA and fecal immunochemical test for colorectal cancer detection

Group

N

CEA

KRAS(+)

BMP3(+)

NDRG4(+)

FOB(+)

Complex value

Sex

       

Female

211

4.52 ± 1.06

14.69%

8.53%

22.27%

9.48%

221.7 ± 22.34

Male

148

4.53 ± 1.67

18.24%

11.49%

18.24%

15.54%

302.9 ± 33.27

P value

 

0.996

0.385

0.371

0.427

0.10

0.168

Age

       

 ≥ 60y

114

6.31 ± 2.30

21.05%

14.91%

34.21%

16.67%

341.4 ± 40.02

 < 60y

245

3.69 ± 0.84

13.88%

7.35%

19.18%

8.57%

207.5 ± 19.46

P value

 

0.188

0.092

0.034

0.003

0.03

0.004

The classification

CRC

49

10.22 ± 4.53

46.94%

53.06%

81.63%

73.47%

1011 ± 50.38

AA

27

2.47 ± 0.23

22.22%

0

11.11%

7.41%

163.2 ± 37.94

NA

65

2.73 ± 0.20

15.38%

10.77%

18.46%

21.54%

162.3 ± 21.94

Other cancer

28

15.12 ± 8.6

14.29%

0

14.29%

3.57%

125.4 ± 23.92

Healthy Controls

190

2.38 ± 0.11

8.42%

1.58%

14.74%

1.58%

115.3 ± 8.8

P value

 

 < 0.001*, 0.76$, 0.105&, < 0.001#

 < 0.001*, 0.038$, 0.152&, 0.30#

 < 0.001*, 0.999$, 0.033&, 0.999#

 < 0.001*, 0.774$, 0.553&, 0.999#

 < 0.001*, 0.118$, 0.001&, 0.425#

 < 0.001*, 0.041$, 0.018&, 0.683#

  1. *The comparison of CRC patients versus healthy controls
  2. $The comparison of AA patients versus healthy controls
  3. &The comparison of the NA patients versus healthy controls
  4. #The comparison of the other cancer patients versus healthy controls