Poorly differentiated cluster grade-a vital predictor for lymph node metastasis and oncological outcomes in patients with T1 colorectal cancer: a retrospective study

Table 3 Univariate analyses of the potential predictors of lymph node metastasis

Parameters	Crude OR (95% CI)	AIC	P
PDC grade		61.626	< 0.001
G 1	Reference
G 2	0.038 (0.004, 0.331)		0.003
G 3	0.002 (< 0.001, 0.018)		< 0.001
Depth of submucosal invasion		101.793	< 0.001
> 1 mm	Reference
≤ 1 mm	15.326 (4.282, 54.855)
Stratification of submucosal invasion		112.951	0.002
SM 1	Reference
SM 2	10.303 (2.315, 45.848)
Tumor size (mm)		127.937	0.566
≤ 20	Reference
> 20	0.732 (0.252, 2.123)
TB grade		87.953	< 0.001
Bd 1	Reference
Bd 2	0.088 (0.022, 0.351)		0.001
Bd 3	0.013 (0.003, 0.063)		< 0.001
Tumor grade (WHO)		125.464	0.319
1	Reference
2	0.435 (0.095, 1.990)		0.283
3	1.467 (0.125, 17.213)		0.761
PNI		115.270	< 0.001
Absence	Reference
Presence	0.109 (0.035, 0.339)
LVI		118.567	0.001
Absence	Reference
Presence	0.136 (0.042, 0.439)
Mucinous composition		127.929	0.539
Absence	Reference
Presence	0.539 (0.660, 0.175)
Tumor location		124.534	0.943
Right colon	Reference
Left colon	< 0.001 (< 0.001, –*)		0.999
Rectum	< 0.001 (< 0.001, –*)		0.999
Number of lesions		127.919	0.519
Unifocal	Reference
Multifocal	0.478 (0.051, 4.500)
Operate method			0.541
Laparotomy	Reference
Laparoscopy	0.745 (0.289, 1.918)

OR odds ratio, CI confidence interval, AIC Akaike information criterion, PDC poorly differentiated cluster, TB tumor budding, PNI perineural invasion, LVI lymphvascular invasion
* represent the missing values

ISSN: 1471-230X