Table 2 KRAS mutation status and frequency of mutation types
N | % | |
|---|---|---|
Status | ||
Mutation | 214 | 51.7 |
Wild-type | 193 | 46.6 |
Unknow (invalid test) | 7 | 1.7 |
Mutation | ||
Codon 12 c.35G > T (p.Gly12Val) c.35G > A (p.Gly12Asp) c.34G > T (p.Gly12Cys) c.34G > C (p.Gly12Arg) c.34G > A (p.Gly12Ser) c.35G > C (p.Gly12Ala) | 168 61 54 23 11 10 9 | 78.5 28.5 25.2 10.7 5.1 4.7 4.2 |
Codon 13 c.38G > A (p.Gly13Asp) | 25 | 11.7 |
Codon 146 c.436G > C/c.436G > A/c.437 C > T (p.Ala146Pro/p.Ala146Thr/p.Ala146Val) | 16 | 7.5 |
Codon 59 c.175G > A / c.176 C > A / c.176 C > G (p.Ala59Thr/p.Ala59Val/ p.Ala59Gly) | 1 | 0.5 |
Codon 61 c.182 A > G (p.Gln61Arg) | 4 | 1.9 |