Table 4 Association between KRAS status and clinicopathological features (n = 407/414)
| Â | Mutation n (%) | Wild-type n (%) | p value |
|---|---|---|---|
Age, years | Â | Â | 0.28 |
≤ 60 (n = 195) | 99 (50.8) | 96 (49.2) |  |
> 60 (n = 212) | 119 (56.1) | 93 (43.9) |  |
Gender | Â | Â | 0.45 |
Female (n = 195) | 100 (51.3) | 95 (48.7) |  |
Male (n = 212) | 114 (53.8) | 98 (46.2) |  |
Primary tumor site | Â | Â | 0.08 |
Left-sided colon | 150 (50.2) | 149 (49.8) | Â |
Right-sided colon | 63 (60) | 42 (40) | Â |
Not specified | 1 (0.33) | 2 (0.67) | Â |
Histological type | Â | Â | 0.79 |
Adenocarcinoma, NOS (n = 366) | 190 (51.9) | 176 (48.1) |  |
Mucinous adenocarcinoma (n = 34) | 20 (58.8) | 14 (41.2) |  |
Poorly cohesive carcinoma (n = 4) | 3 (75) | 1 (25) |  |
Neuroendocrine small cell carcinoma (n = 3) | 1 (33.3) | 2 (66.7) |  |
Tumor differentiation | Â | Â | 0.21 |
Well differentiated (n = 152) | 83 (54.6) | 69 (45.4) |  |
Moderately differentiated (n = 220) | 119 (54.1) | 101 (45.9) |  |
Poorly differentiated (n = 35) | 12 (34.3) | 23 (65.7) |  |