Table 5 Association between NRAS status and clinicopathological features (n = 401/414)
| Â | Mutation n (%) | Wild-type n (%) | p value |
|---|---|---|---|
Age, years | Â | Â | 0.005 |
≤ 60 (n = 193) | 1 (0.5) | 192 (99.5) |  |
> 60 (n = 208) | 11 (5.3) | 197 (94.7) |  |
Gender | Â | Â | 0.64 |
Female (n = 194) | 5 (2.6) | 189 (97.4) |  |
Male (n = 207) | 7 (3.4) | 200 (96.6) |  |
Primary tumor site | Â | Â | 0.44 |
Left-sided colon | 10 (3.4) | 285 (96.6) | Â |
Right-sided colon | 2 (1.9) | 103 (98.1) | Â |
Not specified | 0 (0) | 1 (100) | Â |
Histological type | Â | Â | 0.49 |
Adenocarcinoma, NOS (n = 360) | 12 (3.3) | 348 (96.7) |  |
Mucinous adenocarcinoma (n = 34) | 0 | 34 (100) |  |
Poorly cohesive carcinoma (n = 4) | 0 | 4 (100) |  |
Neuroendocrine small cell carcinoma (n = 3) | 0 | 3 (100) |  |
Tumor differentiation | Â | Â | 0.79 |
Well differentiated (n = 150) | 8 (5.3) | 142 (94.7) |  |
Moderately differentiated (n = 217) | 4 (1.8) | 213 (98.2) |  |
Poorly differentiated (n = 34) | 0 | 34 (100) |  |