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Table 1 Patients´ characteristics and characteristics of ERCs

From: Transmission of oral microbiota to the biliary tract during endoscopic retrograde cholangiography

 

Total

Cholangitis

No Cholangitis

p-value

Number of patients (%)

49 (100%)

16 (32.7%)

33 (67.4%)

–-

Number of female patients

11 (21.4%)

4 (7.4%)

7 (14.4%)

0.394

Age (years)

61.4 ± 11.6

62.3 ± 12.8

60.7 ± 8.4

0.341

Smoker

18 (36.7%)

6 (37.5%)

12 (36.3%)

0.519

EPT before inclusion

21 (42.9%)

9 (56.1%)

12 (36.4%)

0.134

EPT during the study period

28 (57.1%)

7 (43.2%)

21 (63.6%)

0.213

Diabetes mellitus

8 (16.3%)

3 (18.8%)

5 (15.2%)

0.732

Malignant disease

10 (20.4%)

4 (25%)

6 (18.2%)

0.659

Malignant disease causing bile duct stenosis

7 (14,3%)

2 (12.5%)

5 (15.2%)

0.823

OLT prior to study inclusion

17 (34.7%)

4 (25%)

13 (39.4%)

0.501

CRP (mg/dl)

0.95 (0.4–11.3)

6.2 (3.4–11.3)

0.6 (0.4–1)

0.011

AST (U/l)

61 (39–102)

68 (43.8–133.5)

57 (37–80.5)

0.240

ALT (U/l)

51(28–111)

65.5 (35.3–172)

44 (22–79.5)

0.423

Lactate Dehydrogenase (U/l)

247 (128–420)

347 (204.8–607.2)

200 (87–377)

0.447

Alkaline Phosphatase (U/l)

226 (142–421)

295 (218.8)

184 (126–328)

0.550

Leucocytes (g/l)

6.7 (4.7–8.9)

7.7 (5.3–12.9)

5.8 (4.6–7.7)

0.170

Bilirubin (mg/dl)

1.4 (0.7–3.3)

2.8 (1.7–5.3)

1.02 (0.6–2.1)

0.375

Total number of ERCs

99

34 (100%)

65 (100%)

 

Suspected bile duct stenosis

86

32 (94.1%)

54 (83.1%)

0.122

Suspected bile duct stricture after OLT

41

32 (94.1%)

9 (13.8%)

0.029

Malignant disease causing stenosis

18

7 (20.6%)

11 (16.9%)

0.653

Suspected choledocholithiasis

11

7 (20.6%)

4 (6.2%)

0.030

Stent overall

53

19 (55.9%)

34 (52.3%)

0.735

plastic stent

40

16 (47.1%)

24 (36.9%)

0.329

metal stent

6

2 (5.9%)

4 (6.2%)

0.957

Metal stent recanalization

7

2 (12.5%)

5 (15.5%)

0.832

Received antibiotic therapy Pre ERC

40

21 (61.8%)

19 (29.2%)

0.002

Received antibiotic therapy post ERC

94

34 (100%)

60 (92.3%)

0.097

Overlapping microbial analysis (oral cavity/biliary system)

33

14 (41.2%)

19 (29.2%)

0.265

Overlapping microbial analysis (pre ERC duodenoscope/biliary system)

12

4 (11.8%)

8 (12.3%)

0.841

Overlapping microbial analysis (oral cavity/pre ERC duodenoscope/biliary system)

7

3(8.8%)

4 (6.1%)

0.688

Overlapping microbial analysis (biliary system/post ERC duodenoscope)

78

27 (79.4%)

51 (79.6%)

0.431

Overlapping microbial analysis (oral cavity/pre ERC duodenoscope /biliary system/post ERC duodenoscope)

3

1 (2.9%)

2(3.1%)

0.999