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Table 1 Baseline characteristics of 85 patients with advanced hepatocellular carcinoma who received atezolizumab plus bevacizumab

From: Hyperprogressive disease during atezolizumab plus bevacizumab treatment in patients with advanced hepatocellular carcinoma from Japanese real-world practice

Characteristic

N = 85

Sex, male, n (%)

73 (85.9)

Age > 74, n (%)

41 (48.2)

HBV positive, n (%)

18 (21.2)

HCV positive, n (%)

25 (29.4)

Child–Pugh class A, n (%)

79 (92.9)

AFP > 400 ng/mL, n (%)

32 (37.6)

BCLC stage C, n (%)

52 (61.2)

Macrovascular invasion, n (%)

18 (21.2)

Extrahepatic spread, n (%)

35 (41.2)

Treatment line, atezolizumab plus bevacizumab,1st line, n (%)

39 (45.9)

ECOG-PS ≤ 1, n (%)

85 (100)

NLR ≥ 3.43, n (%)

35 (41.2)

  1. Abbreviations: HBV hepatitis B virus, HCV hepatitis C virus, AFP alpha-fetoprotein, BCLC Barcelona Clinic Liver Cancer, ECOG-PS Eastern Cooperative Oncology Group Performance Status, NLR neutrophil-to-lymphocyte ratio