Table 3 Results of publications of full economics evaluations for liver metastases from colorectal cancer (lmCRC)
Author, year publication (year cost) | Comparators | Costs | Health Outcomes | Ratio cost / Outcome’s health | |||||
|---|---|---|---|---|---|---|---|---|---|
Original cost | Adjusted to $US PPP [21] | LYG | QALY | ICER | ICUR | ICER $US PPP/LYG | ICUR $US PPP /QALY | ||
WTP | |||||||||
Y-90 TARE vs. BSC | |||||||||
Bester, 2013 [23] (2012) | Y-90 TARE | £ 35,487 | 39,221 | 2.09 | 1.50 | Y-90 TARE vs. BSC | Y-90 TARE vs. BSC | Y-90 TARE vs. BSC | Y-90 TARE vs. BSC |
BSC | £ 12,730 | 14,069 | 0.97 | 0.69 | £ 20,323 | £ 28,216 | 22,461 | 31,185 | |
Difference Δ | Δ £ 22,757 | Δ 25,151 | Δ 1.12 | Δ 0.81 | WTP (£30,000/QALY): 57% | ||||
Cosimelli, 2013 [24] (2012)a | Y-90 TARE | € 39,973 | 41,099 | 2.12 | 1.52 | Y-90 TARE vs. BSC | Y-90 TARE vs. BSC | Y-90 TARE vs. BSC | Y-90 TARE vs. BSC |
BSC | € 15,347 | 15,779 | 0.98 | 0.70 | ND | € 29,850 | ND | 30,691 | |
Difference Δ | Δ € 24,626 | Δ 25,320 | Δ 1.35 | Δ 0.83 | WTP (€50,000/QALY): 57% | ||||
Pennington, 2015 [25] (2013)a | Y-90 TARE | £ 35,487 | 38,592 | 2.09 | 1.50 | Y-90 TARE vs. BSC | Y-90 TARE vs. BSC | Y-90 TARE vs. BSC | Y-90 TARE vs. BSC |
BSC | £ 12,730 | 13,844 | 0.97 | 0.69 | £ 20,323 | £ 28,216 | 22,101 | 30,684 | |
Difference Δ | Δ £ 22,757 | Δ 24,748 | Δ 1.12 | Δ 0.81 | WTP (£30,000/QALY): 57% | ||||
Brennan, 2020 [26] (2019) | Y-90 TARE | £ 34,168 | 34,810 | ND | 1.50 | Y-90 TARE vs. BSC | Y-90 TARE vs. BSC | Y-90 TARE vs. BSC | Y-90 TARE vs. BSC |
BSC | £ 15,268 | 15,268 | ND | 0.69 | £ 18,900 | £ 23,435 | 19,255 | 23,875 | |
Difference Δ | Δ £ 18,900 | Δ 19,255 | Δ ND | Δ 0.81 | WTP (£30,000/QALY): 56% | ||||
Y-90 TARE vs. HAI | |||||||||
Loveman, 2014 [27] (2012) | Y-90 TARE + HAI | £ 18,955 | 20,949 | 1.86 | 1.41 | Y-90 TARE + HAI vs. HAI | Y-90 TARE + HAI vs. HAI | Y-90 TARE + HAI vs. HAI | Y-90 TARE + HAI vs. HAI |
HAI | £ 6,010 | 6,642 | 1.49 | 1.06 | £ 35,225 | £ 37,303 | 38,931 | 41,228 | |
Difference Δ | Δ £ 12,945 | Δ 14,307 | Δ 0.37 | Δ 0.35 | WTP (£30,000/QALY): 26% | ||||