Table 2 Univariate and multivariate analysis

Age

 < 40

Ref

NA

Ref

NA

40 ~ 60

1.346(0.648 ~ 2.795)

0.796(0.43)

1.638(0.803 ~ 3.342)

1.356(0.17)

60 ~ 

1.653(0.808 ~ 1.106)

1.375(0.17)

2.189(1.089 ~ 4.399)

2.2(0.03)

Marriage

Married

Ref

NA

Ref

NA

Divorced

1.133(1.044 ~ 1.230)

3.004(< 0.01)

1.014(0.93 ~ 1.106)

0.323(0.75)

Single

1.214(1.130 ~ 1.303)

5.342(< 0.01)

1.304(1.201 ~ 1.415)

6.339(< 0.01)

Other

1.224(1.119 ~ 1.339)

4.422(< 0.01)

1.108(1.006 ~ 1.22)

2.081(0.04)

Race

White

Ref

NA

Ref

NA

Black

1.174(1.084 ~ 1.270)

3.958(< 0.01)

1.162(1.068 ~ 1.264)

3.492(< 0.01)

Other

0.978(0.865 ~ 1.106)

-0.355(0.72)

1.017(0.895 ~ 1.156)

0.262(0.79)

Sex

Female

Ref

NA

Ref

NA

Male

1.007(0.952 ~ 1.064)

0.231(0.82)

1.048(0.985 ~ 1.115)

1.473(0.14)

Behav

Behav1

Ref

NA

Ref

NA

Behav2

0.542(0.486 ~ 0.604)

-11.059(< 0.01)

0.945(0.841 ~ 1.063)

-0.944(0.35)

Behav3

1.028(0.938 ~ 1.127)

0.599(0.55)

1.009(0.921 ~ 1.106)

0.201(0.84)

Behav4

0.478(0.407 ~ 0.562)

-8.960(< 0.01)

0.773(0.652 ~ 0.916)

-2.967(< 0.01)

Other

1.292(1.168 ~ 1.429)

4.992(< 0.01)

1.119(0.995 ~ 1.259)

1.883(0.06)

Grade

I

Ref

NA

Ref

NA

II

1.678(1.464 ~ 1.922)

7.456(< 0.01)

1.094(0.958 ~ 1.249)

1.32(0.19)

III

3.228(2.802 ~ 3.792)

16.221(< 0.01)

1.338(1.161 ~ 1.542)

4.026(< 0.01)

IV

3.459(2.917 ~ 4.102)

14.267(< 0.01)

1.283(1.071 ~ 1.537)

2.702(0.01)

Stage

I

Ref

NA

Ref

NA

II

2.508(2.179 ~ 2.889)

12.795(< 0.01)

1.419(1.161 ~ 1.734)

3.415(< 0.01)

III

6.391(5.608 ~ 7.282)

27.831(< 0.01)

3.68(2.914 ~ 4.648)

10.942(< 0.01)

IV

26.820(23.538 ~ 30.560)

49.387(< 0.01)

9.704(7.634 ~ 12.335)

18.566(< 0.01)

Tstage

T1

Ref

NA

Ref

NA

T2

1.056(0.875 ~ 1.273)

0.569((0.57)

1.14(0.942 ~ 1.378)

1.345(0.18)

T3

3.311(2.841 ~ 3.858)

15.330(< 0.01)

1.759(1.445 ~ 2.141)

5.626(< 0.01)

T4

8.809(7.549 ~ 10.278)

27.639(< 0.01)

3.029(2.48 ~ 3.7)

10.866(< 0.01)

Nstage

N0

Ref

NA

Ref

NA

N1

3.075(2.854 ~ 3.314)

29.486(< 0.01)

0.74(0.58 ~ 0.945)

-2.415(0.02)

N2

6.890(6.428 ~ 7.386)

54.482(< 0.01)

0.792(0.585 ~ 1.073)

-1.504(0.13)

Surgery

Surg1

Ref

NA

Ref

NA

Surg2

0.936(0.866 ~ 1.012)

-1.657(0.098)

1.047(0.964 ~ 1.136)

1.090(0.28)

Surg3

4.172(3.489 ~ 4.988)

15.662(< 0.01)

2.252(1.56 ~ 3.251)

4.333(< 0.01)

Surg4

1.280(1.084 ~ 1.510)

2.920(0.003)

0.942(0.789 ~ 1.124)

-0.664(0.51)

LNSur

4 ~ 

Ref

NA

Ref

NA

1 ~ 3

1.884(1.637 ~ 2.169)

8.823(< 0.01)

0.927(0.705 ~ 1.219)

-0.54(0.59)

None

1.400(1.164 ~ 1.680)

3.590(< 0.01)

1.252(1.021 ~ 1.535)

2.161(0.03)

SurgOth

None

Ref

NA

Ref

NA

Yes

2.431(2.243 ~ 2.634)

21.678(< 0.01)

0.956(0.873 ~ 1.048)

-0.954(0.34)

Radiation

None

Ref

NA

Ref

NA

Yes

2.219(1.890 ~ 2.605)

9.749(< 0.01)

1.167(0.968 ~ 1.407)

1.624(0.10)

Chemotherapy

None

Ref

NA

Ref

NA

Yes

0.455(0.431 ~ 0.482)

-27.591(< 0.01)

1.554(1.444 ~ 1.672)

11.774(< 0.01)

Deposits

None

Ref

NA

Ref

NA

Yes

1.586(1.479 ~ 1.702)

18.878(< 0.01)

1.179(1.093 ~ 1.272)

4.253(< 0.01)

LnPositive

No

Ref

NA

Ref

NA

1 ~ 3

3.025(2.801 ~ 3.268)

28.119(< 0.01)

1.311(1.044 ~ 1.646)

2.335(0.02)

4 ~ 6

4.451(4.998 ~ 5.945)

38.318(< 0.01)

1.714(1.276 ~ 2.3)

3.584(< 0.01)

 > 7

8.537(7.909 ~ 9.214)

55.064(< 0.01)

2.234(1.681 ~ 2.971)

5.534(< 0.01)

Bone

None

Ref

NA

Ref

NA

Yes

6.977(5.267 ~ 9.242)

13.544(< 0.01)

1.23(0.879 ~ 1.722)

1.208(0.23)

Brain

None

Ref

NA

Ref

NA

Yes

8.483(5.457 ~ 13.186)

9.500(< 0.01)

1.521(0.827 ~ 2.797)

1.35(0.18)

Liver

None

Ref

NA

Ref

NA

Yes

6.956(6.541 ~ 7.398)

61.225(< 0.01)

1.446(1.302 ~ 1.605)

6.898(< 0.01)

Lung

None

Ref

NA

Ref

NA

Yes

5.844(5.281 ~ 6.468)

34.124(< 0.01)

1.206(1.064 ~ 1.367)

2.924(< 0.01)

Size

 < 3 cm

Ref

NA

Ref

NA

3 ~ 5 cm

1.088(1.001 ~ 1.173)

2.186(0.03)

0.979(0.902 ~ 1.062)

-0.514(0.61)

 > 5 cm

1.172(1.096 ~ 1.254)

4.621(< 0.01)

0.959(0.893 ~ 1.029)

-1.158(0.25)