From: Nomogram predicts risk of perineural invasion based on serum biomarkers for pancreatic cancer
Characteristics | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
B | HR (95% CI) | P value | B | HR (95% CI) | P value | |
Age, > 60 vs. ≤ 60, years | 0.143 | 1.154 (0.700-1.902) | 0.574 |  |  |  |
Gender, female vs. male | -0.379 | 0.685 (0.409–1.147) | 0.150 |  |  |  |
BMI, per kg/m2 | 0.011 | 1.011 (0.928-1.100) | 0.808 | Â | Â | Â |
ASA grade, III vs. ≤ II | 0.101 | 1.107 (0.542–2.261) | 0.781 |  |  |  |
Biliary infection, yes vs. no | 0.051 | 1.052 (0.257–4.305) | 0.944 |  |  |  |
Obstructive jaundice, yes vs. no | 0.988 | 2.687 (1.598–4.518) | < 0.001 |  |  |  |
Weight-loss ≥ 5 kg, yes vs. no | -0.189 | 0.828 (0.394–1.739) | 0.618 |  |  |  |
Preoperative Hb, per g/L | -0.015 | 0.985 (0.968–1.002) | 0.084 |  |  |  |
Preoperative BG per mmol/L | 0.457 | 1.579 (1.283–1.943) | < 0.001 | 0.336 | 1.399 (1.144–1.710) | 0.001 |
Preoperative ALB, per g/L | -0.073 | 0.930 (0.869–0.995) | 0.034 | 0.010 | 1.010 (0.932–1.095) | 0.808 |
Preoperative TBIL per µmol/L | 0.007 | 1.007 (1.004–1.010) | < 0.001 | 0.004 | 1.004 (1.000-1.007) | 0.029 |
Preoperative CA19-9, per U/mL | 0.002 | 1.002 (1.001–1.004) | < 0.001 | 0.002 | 1.002 (1.000-1.003) | 0.010 |
Preoperative CEA, per ng/mL | 0.017 | 1.018 (0.962–1.076) | 0.541 |  |  |  |
Preoperative CA125, per U/mL | 0.025 | 1.025 (1.001–1.050) | 0.040 | 0.010 | 1.010 (0.988–1.031) | 0.381 |
Preoperative FIB, per g/L | 0.472 | 1.603 (1.245–2.064) | < 0.001 | 0.093 | 1.097 (0.795–1.514) | 0.573 |
Maximum tumor size, per cm †| -0.080 | 0.923 (0.764–1.115) | 0.407 |  |  |  |