Not histological healing N = 70 (GS > = 2) | Histological healing N = 21 (GS < 2) | P-Value | Histological active N = 65 (GS > = 3.1) | Histological inactive N = 26 (GS < 3.1) | P-Value | |
---|---|---|---|---|---|---|
Age, year, mean (SD) | 46.71 (14.71) | 51.81 (9.72) | 0.067 | 46.82 (14.45) | 50.58 (10.25) | 0.230 |
Gender (male, %) | 43 (61.43) | 12 (57.14) | 0.725 | 41 (63.08) | 14 (53.85) | 0.416 |
Hematochezia (%) | 60 (85.71) | 7 (33.33) | < 0.001 | 55 (84.62) | 12 (42.86) | < 0.001 |
Disease duration of UC, years (SD) | 3.70 (4.15) | 7.80 (10.07) | 0.082 | 3.64 (4.11) | 7.15 (9.34) | 0.076 |
Newly diagnosed cases (%) | 10 (14.29) | 1 (5.00) | 0.240 | 8 (12.31) | 3 (11.54) | 0.919 |
Hospital stay length, days (SD) | 13.55 (11.31) | 6.57 (6.46) | 0.008 | 13.89 (11.64) | 7.07 (6.09) | 0.006 |
WBC, *10^9/L, (SD) | 7.86 (3.01) | 5.55 (1.54) | < 0.001 | 8.02 (2.99) | 5.60 (1.78) | < 0.001 |
Hemoglobin, g/L, (SD) | 113.66 (26.63) | 133.71 (16.88) | < 0.001 | 113.69 (26.79) | 129.77 (20.37) | 0.007 |
Hct, %, (SD) | 35.20 (7.22) | 40.58 (4.28) | < 0.001 | 35.22 (7.34) | 39.48 (5.06) | 0.002 |
Platelet count, *10^9/L, (SD) | 313.23 (110.52) | 224.52 (57.63) | < 0.001 | 320.80 (111.08) | 222.65 (52.09) | < 0.001 |
C-reactive protein, mg/L, (SD) | 38.02 (50.26) | 4.51 (8.67) | < 0.001 | 40.80 (51.12) | 4.00 (7.88) | < 0.001 |
ESR, mm/h, (SD) | 23.76 (21.28) | 8.57 (6.08) | < 0.001 | 24.33 (21.76) | 10.04 (8.01) | < 0.001 |
D-dimer, µg/L, (SD) | 1658.13 (3661.47) | 578.53 (623.96) | 0.184 | 1752.25 (3784.29) | 550.85 (576.66) | 0.015 |
Albumin, g/L, (SD) | 36.48 (6.21) | 41.00 (6.22) | 0.004 | 36.20 (6.28) | 40.81 (5.80) | 0.002 |
Fecal Calprotectin (μg/g) | N = 43 | N = 7 | N = 41 | N = 9 | ||
273.08 (268.56) | 294.21 (434.10) | 0.861 | 310.69 (304.19) | 118.19 (153.20) | 0.072 | |
Current therapy by 5-ASA (%) | 59 (84.29) | 18 (85.71) | 0.874 | 56 (86.15) | 21 (80.77) | 0.520 |
Current corticosteroids drugs (%) | 10 (14.29) | 1 (4.76) | 0.240 | 9 (13.85) | 2 (7.69) | 0.416 |
Current anti-TNF treatment (%) | 1 (1.43) | 0 (0) | 0.582 | 1 (1.54) | 0 (0) | 0.525 |