The predictive value of CD4, CD8, and C—reactive protein in the prognosis of schistosomal and non-schistosomal colorectal cancer

Table 2 Densities and cut-off values of the tumour infiltrating lymphocytes

	Density (cell/mm²)	Median value	Cutoff value	Low-density group(%)
iCD4	0–1857	74	29	31
sCD4	0–944	203	145	38
iCD8	0–2554	291	77	19
sCD8	0–2803	462	645	68

X-tile analysis of overall survival (OS) was performed using patients’ data collected from the pathological system of the Qingpu District Center for Disease Control and Prevention to determine the optimal cut-off value for iCD4, sCD4, iCD8, sCD8 density. The optimal cut-off value for iCD4 density was 29.0, for sCD4 was 145.0, for iCD8 was 77 and for sCD8 was 645 cell/mm². Patients were divided into two groups: low-density group and high-density group based on the cutoff value of TILs

ISSN: 1471-230X