Table 3 Univariate and multivariate analysis for baseline predictors of hepatic decompensation

Age

1.038 (1.014–1.062)

0.001

1.042 (1.013–1.072)

0.005

Males

0.820 (0.510–1.319)

0.414

Etiology of cirrhosis

 Hepatitis B

Reference

Reference

 Hepatitis C

1.895 (0.983–3.652)

0.056

1.433 (0.706, 2.906)

0.319

 Autoimmune

1.662 (0.591–4.680)

0.336

1.732 (0.540, 5.553)

0.356

 Alcohol

4.309 (1.911–9.715)

< 0.001

2.447 (1.018, 5.883)

0.046

 Others

3.040 (1.543–5.988)

0.001

3.601 (1.709, 7.586)

0.001

Small esophageal varices

5.143 (2.858, 9.256)

< 0.001

3.341 (1.770, 6.306)

< 0.001

ALT

0.999 (0.997–1.001)

0.219

AST

1.000 (0.998–1.001)

0.723

ALP

1.003 (1.001–1.004)

0.003

1.001 (0.997–1.006)

0.607

GGT

1.001 (1.001–1.002)

< 0.001

1.001 (1.001–1.002)

0.004

ALB

0.914 (0.879–0.950)

< 0.001

0.981 (0.936–1.028)

0.420

TBIL

1.003 (0.997–1.009)

0.348

Cr

0.986 (0.969–1.003)

0.113

INR

1.128 (0.946–1.346)

0.180

PLT

0.983 (0.977–0.988)

< 0.001

0.985 (0.978–0.992)

< 0.001

MELD score

1.098 (1.047–1.151)

< 0.001

0.989 (0.901–1.085)

0.813

APRI

1.034 (0.998–1.072)

0.067

FIB-4 index

1.086 (1.050–1.124)

< 0.001

0.934 (0.857–1.018)

0.119

HA

1.000 (1.000-1.001)

0.591

LN

1.015 (1.011–1.020)

< 0.001

1.008 (1.002–1.014)

0.011

CIV

1.007 (1.005–1.009)

< 0.001

1.004 (1.001–1.007)

0.003

PIIINP

1.023 (0.996–1.052)

0.100