Table 4 Univariate and multivariate analysis for baseline predictors of hepatic decompensation in HBV-related cirrhosis

Age

1.046 (1.014–1.080)

0.005

1.054 (1.015–1.095)

0.007

Males

1.355 (0.693–2.649)

0.375

Small esophageal varices

6.424 (2.660-15.513)

< 0.001

2.855 (1.139–7.158)

0.025

ALT

0.992 (0.985-1.000)

0.054

AST

0.994 (0.988–1.001)

0.111

HBV DNA

0.973 (0.836–1.133)

0.727

qHBsAg (× 10³)

0.810 (0.672–0.977)

0.027

0.883 (0.731–1.066)

0.196

HBeAg positive

1.044 (0.530–2.056)

0.901

Received antiviral therapy

1.213 (0.166–8.873)

0.849

ALB

0.899 (0.852–0.948)

< 0.001

1.032 (0.956–1.113)

0.423

TBIL

1.006 (0.992–1.020)

0.431

Cr

0.988 (0.964–1.013)

0.346

PLT

0.972 (0.963–0.981)

< 0.001

0.975 (0.962–0.988)

< 0.001

MELD score

1.167 (1.064–1.281)

0.001

0.946 (0.816–1.095)

0.456

APRI

0.988 (0.884–1.104)

0.830

FIB-4 index

1.131 (1.073–1.192)

< 0.001

0.929 (0.803–1.075)

0.322

HA

1.000 (1.000-1.001)

0.621

LN

1.016 (1.009–1.022)

< 0.001

1.012 (1.002–1.022)

0.015

CIV

1.007 (1.004–1.009)

< 0.001

1.005 (1.001–1.008)

0.024

PIIINP

1.018 (0.980–1.057)

0.362