Table 1 Baseline characteristics
Variable | Overall (n = 111) | Non-surgery (n = 88) | Surgery (n = 23) | p-valuea |
|---|---|---|---|---|
Gender | 0.576 | |||
Male | 87 (78.4) | 70 (79.5) | 17 (73.9) | |
Female | 24 (21.6) | 18 (20.5) | 6 (26.1) | |
Age at diagnosis | 0.682 | |||
A1: < 16 years | 5 (4.5) | 5 (5.7) | 0 (0.0) | |
A2: 16–40 years | 81 (73.0) | 64 (72.7) | 17 (73.9) | |
A3: >40 years | 25 (22.5) | 19 (21.6) | 6 (26.1) | |
Age at BAE, years† | 33 (25, 42) | 32 (24, 41) | 35 (32, 49) | 0.046 |
Disease duration, years† | 1 (0, 6) | 0 (0, 5) | 5 (0, 10) | 0.010 |
Location | 0.834 | |||
L1: ileal | 81 (73.0) | 63 (71.6) | 18 (78.3) | |
L3: ileocolonic | 29 (26.1) | 24 (27.3) | 5 (21.7) | |
Upper disease | 21 (18.9) | 16 (18.2) | 5 (21.7) | 0.766 |
Behavior | 0.002 | |||
B1: inflammatory | 37 (33.3) | 36 (40.9) | 1 (4.3) | |
B2: stricturing | 56 (50.5) | 41 (46.6) | 15 (65.2) | |
B3: penetrating | 18 (16.2) | 11 (12.5) | 7 (30.4) | |
Perianal disease | 16 (14.1) | 9 (10.2) | 7 (30.4) | 0.022 |
Current or Ex-smoking | 27 (24.3) | 19 (21.6) | 8 (34.8) | 0.189 |
SBRA or segmental colectomy | 23 (20.7) | 16(18.2) | 7 (30.4) | 0.248 |
Harvey-Bradshaw Index † | 0.041 | |||
Remission | 53 (47.7) | 45 (51.1) | 8 (34.8) | |
Mild | 28 (25.2) | 24 (27.3) | 4 (17.4) | |
Moderate to severe | 30 (27.0) | 19 (21.6) | 11 (47.8) | |
Laboratory data† | ||||
Hemogloblin, g/dL | 12.2 (10.3, 13.4) | 12.4 (10.4, 13.4) | 11.7 (8.9, 12.8) | 0.166 |
Albumin, g/dL | 4.2 (3.5, 4.6) | 4.3 (3.6, 4.6) | 3.9 (3.4, 4.3) | 0.073 |
ESR, mg/L | 10.0 (4.0, 21.0) | 9.0 (4.0, 18.0) | 14.0 (5.0, 34.0) | 0.055 |
CRP, mg/L | 0.2 (0.1, 0.6) | 0.1 (0.1, 0.5) | 0.4 (0.2, 1.2) | 0.004 |
Concomitant treatment | ||||
Immunomodulators | 42 (37.8) | 32 (36.4) | 10 (43.5) | 0.531 |
Biologics | 31 (27.9) | 21 (23.9) | 10 (43.5) | 0.062 |
Balloon dilatation at BAE | 43 (38.7) | 28 (31.8) | 15 (65.2) | 0.003 |
Follow-up duration, months†* | 23 (15, 33) | 23 (14, 32) | 23 (15, 33) | 0.456 |