Table 2 Surgical outcomes according to the endoscopic assessment of disease activity
Overall | Total N | Surgery, n (%) | HR (95% CI) | p-valuea | |
|---|---|---|---|---|---|
Small-bowel SES-CD | 0–6 | 38 | 2 (5.3) | 1 | |
7–12 | 73 | 21 (28.8) | 6.31 (1.48–26.91) | 0.013 | |
Any ulcer | No | 10 | 1 (10.0) | 1 | |
Yes | 101 | 22 (21.8) | 2.29 (0.31–17.06) | 0.419 | |
Stenosis | No | 28 | 1 (3.6) | 1 | |
Single or multiple, can be passed | 21 | 1 (4.8) | 1.41 (0.09–22.55) | 0.808 | |
Cannot be passed | 62 | 21 (33.9) | 12.34 (1.66–91.92) | 0.014 | |
Biologics naïve | |||||
Small-bowel SES-CD | 0–6 | 27 | 1 (3.7) | 1 | |
7–12 | 53 | 12 (22.6) | 6.94 (0.90-53.35) | 0.063 | |
Any ulcer | No | 3 | 0 (0.0) | 1 | |
Yes | 77 | 13 (16.9) | 21.42 (0.00-) | 0.621 | |
Stenosis | No | 21 | 1 (4.8) | 1 | |
Single or multiple, can be passed | 18 | 1 (5.6) | 1.18 (0.07–18.92) | 0.905 | |
Cannot be passed | 41 | 11 (26.8) | 6.85 (0.88–53.16) | 0.066 | |
Concomitant biologics | |||||
Small-bowel SES-CD | 0–6 | 11 | 1 (9.1) | 1 | |
7–12 | 20 | 9 (45.0) | 5.02 (0.62–40.36) | 0.130 | |
Any ulcer | No | 7 | 1 (14.3) | 1 | |
Yes | 24 | 9 (37.5) | 2.49 (0.31–19.92) | 0.391 | |
Stenosis | No | 7 | 0 (0.0) | 1 | |
Single or multiple, can be passed | 3 | 0 (0.0) | 1.04 (0.00-) | 0.995 | |
Cannot be passed | 21 | 10 (47.6) | 43.90 (0.07-) | 0.254 |