Table 3 Predictors of the surgery in cox regression analysis in overall patients
Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
HR (95% CI) | p-valuea | HR (95% CI) | p-valuea | |
Small-bowel SES-CD | ||||
0–6 | 1 | 1 | ||
≥ 7 | 6.31 (1.48–26.91) | 0.013 | 7.89 (1.77–35.05) | 0.007 |
Gender | ||||
Male | 1 | |||
Female | 1.43 (0.56–3.65) | 0.450 | ||
Age at diagnosis | 1.01 (0.99–1.04) | 0.456 | ||
Duration of CD (years) | 1.13 (1.05–1.22) | 0.002 | 1.17 (1.07–1.29) | 0.001 |
Upper disease | 1.06 (0.39–2.87) | 0.904 | ||
Perianal disease | 3.89 (1.56–9.66) | 0.003 | 1.75 (0.63–4.87) | 0.286 |
Current or Ex-smoking | 1.72 (0.73–4.10) | 0.218 | ||
SBRA and segmental colectomy | 1.82 (0.75–4.43) | 0.186 | ||
Harvey-Bradshaw Index | ||||
Remission | 1 | 0.065 | ||
Mild | 0.99 (0.30–3.30) | 0.987 | ||
Moderate to severe | 2.71 (1.09–6.75) | 0.032 | ||
Hemogloblin, g/dL | 0.87 (0.72–1.07) | 0.181 | ||
Albumin, g/dL | 0.61 (0.37–1.01) | 0.053 | ||
ESR, mg/L | 1.01 (0.99–1.02) | 0.257 | ||
CRP, mg/L | 1.59 (1.03–2.47) | 0.038 | 1.75 (0.93–3.28) | 0.081 |
Concomitant immunomodulators | 1.43 (0.62–3.26) | 0.402 | ||
Concomitant biologics | 2.11 (0.92–4.81) | 0.077 | ||
Balloon dilatation at BAE | 3.27 (1.38–7.71) | 0.007 | 2.27 (0.69–7.47) | 0.180 |