Table 2 Correlation between PLAC1, Netrin-1 and clinicopathological characteristics of CRC patients with liver metastasis [cases (%)]
Groups |  | PLAC1 |  | χ2 | P | Netrin-1 |  | χ2 | P |
|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Positive 29 | Negative18 | Â | Â | Positive 37 | Negative 10 | Â | Â |
Gender (%) | Male | 17 (58.62) | 10 (55.56) | 0.043 | 0.836 | 21 (56.76) | 6 (60.00) | 0.034 | 0.854 |
| Â | Female | 12 (41.38) | 8 (44.44) | Â | Â | 16 (43.24) | 4 (40.00) | Â | Â |
Age (year) | < 60 | 14 (48.28) | 7 (38.89) | 0.396 | 0.529 | 22 (59.46) | 6 (60.00) | 0.001 | 0.975 |
|  | ≥ 60 | 15 (51.72) | 11 (61.11) |  |  | 15 (40.54) | 4 (40.00) |  |  |
Maximum tumor diameter (cm) | < 5 | 14 (48.28) | 6 (33.33) | 1.014 | 0.314 | 23 (62.16) | 5 (50.00) | 0.484 | 0.487 |
|  | ≥ 5 | 15 (51.72) | 12 (66.67) |  |  | 14 (37.84) | 5 (50.00) |  |  |
Dukes stage (%) | Stage A + B | 19 (65.52) | 11 (61.11) | 0.093 | 0.760 | 9 (24.32) | 6 (60.00) | 4.611 | 0.032 |
| Â | Stage C | 10 (34.48) | 7 (38.89) | Â | Â | 28 (75.68) | 4 (40.00) | Â | Â |
Differentiation degree (%) | Low | 15 (51.72) | 3 (16.67) | 6.255 | 0.044 | 20 (54.05) | 1 (10.00) | 6.288 | 0.043 |
| Â | Medium | 12 (41.38) | 14 (77.78) | Â | Â | 14 (37.84) | 7 (70.00) | Â | Â |
| Â | High | 2 (6.90) | 1 (5.56) | Â | Â | 3 (8.11) | 2 (20.00) | Â | Â |
Lymph node metastasis (%) | Yes | 19 (65.52) | 6 (33.33) | 4.620 | 0.032 | 25 (67.57) | 3 (30.00) | 4.613 | 0.032 |
| Â | No | 10 (34.48) | 12 (66.67) | Â | Â | 12 (32.43) | 7 (70.00) | Â | Â |
Histological type (%) | Adenocarcinoma | 19 (65.52) | 10 (55.56) | 0.479 | 0.787 | 26 (70.27) | 4 (30.00) | 4.114 | 0.128 |
| Â | Mucinous adenocarcinoma | 6 (20.69) | 5 (27.78) | Â | Â | 7 (18.92) | 5 (60.00) | Â | Â |
| Â | other | 4 (13.79) | 3 (16.67) | Â | Â | 4 (10.81) | 1 (10.00) | Â | Â |