Table 3 Univariate analysis of liver metastasis in CRC [(‾x ± s), cases (%)]
Factors |  | Metastatic group (n = 47) | Non-metastatic group (n = 60) | t/χ2 | P |
|---|---|---|---|---|---|
Gender | Male | 30 (63.83) | 34 (56.67) | 0.563 | 0.453 |
| Â | Female | 17 (36.17) | 26 (43.33) | Â | Â |
Age (year) | < 60 | 19 (40.43) | 20 (33.33) | 0.572 | 0.449 |
|  | ≥ 60 | 28 (59.57) | 40 (66.67) |  |  |
Maximum tumor diameter (cm) | < 5 | 16 (34.04) | 34 (56.67) | 1.258 | 0.262 |
|  | ≥ 5 | 31 (65.96) | 26 (43.33) |  |  |
Dukes stage | Stage A + B | 16 (34.04) | 33 (55.00) | 4.663 | 0.031 |
| Â | Stage C | 31 (65.96) | 27 (45.00) | Â | Â |
Degree of differentiation | Low | 25 (53.19) | 14 (23.33) | 12.838 | 0.002 |
| Â | Medium | 15 (31.91) | 21 (35.00) | Â | Â |
| Â | High | 7 (14.89) | 25 (41.67) | Â | Â |
Lymph node metastasis | Yes | 44 (93.62) | 25 (41.67) | 31.058 | < 0.001 |
| Â | None | 3 (6.38) | 35 (58.33) | Â | Â |
Histological type | Adenocarcinoma | 37 (78.72) | 53 (88.33) | 4.267 | 0.118 |
| Â | Mucinous adenocarcinoma | 8 (17.02) | 3 (5.00) | Â | Â |
| Â | other | 2 (4.26) | 4 (6.67) | Â | Â |
CEA (ng/ml) |  | 7.16 ± 2.28 | 6.25 ± 1.81 | 2.302 | 0.023 |
CA199 (kU/L) |  | 42.17 ± 12.96 | 39.64 ± 12.09 | 1.041 | 0.300 |
Alb (g/L) |  | 27.85 ± 4.81 | 31.58 ± 5.36 | 6.301 | < 0.001 |
D-dimer (μg/L) |  | 188.25 ± 46.29 | 169.20 ± 22.65 | 2.792 | 0.006 |