Table 1 Baseline characteristics and complications of patients before and after matching
From: Transjugular liver biopsy: enlarge the indications for liver biopsy with reliable diagnostic quality
Characteristic | Before propensity score matching | After propensity score matching | ||||
|---|---|---|---|---|---|---|
PLB (n = 2711) | TJLB (n = 30) | P | PLB (n = 50) | TJLB (n = 25) | P | |
Age, > 50 years (%) | 1144 (42.2) | 19 (63.3) | 0.020 | 30 (60.0) | 15 (60.0) | 1.000 |
Gender, male (%) | 1508 (55.6) | 17 (56.7) | 0.909 | 28 (56.0) | 14 (56.0) | 1.000 |
Cirrhosis (%) | 202 (7.5) | 8 (26.7) | <0.001 | 17 (34.0) | 8 (32.0) | 0.862 |
PH (%) | 295 (10.9) | 29 (96.7) | <0.001 | 48 (96.0) | 24 (96.0) | 1.000 |
TB (%) | ||||||
≤ 2×ULN | 2176 (80.3) | 19 (63.3) | 0.019 | 35 (70.0) | 18 (72.0) | 0.871 |
2-10×ULN | 459 (16.9) | 9 (30.0) | 11 (22.0) | 5 (20.0) | ||
> 10×ULN | 76 (2.8) | 2 (6.7) | 4 (8.0) | 2 (8.0) | ||
Alb (%) | ||||||
≤ 30 g/l | 44 (1.6) | 2 (6.7) | 0.032 | 4 (8.0) | 2 (8.0) | 1.000 |
> 30 g/l | 2667 (98.4) | 28 (93.3) | 46 (92.0) | 23 (92.0) | ||
ALT (%) | ||||||
≤ 2×ULN | 1622 (59.8) | 26 (86.7) | 0.003 | 48 (96.0) | 23 (92.0) | 0.470 |
2-5×ULN | 692 (25.5) | 3 (10.0) | 2 (4.0) | 2 (8.0) | ||
> 5×ULN | 397 (14.6) | 1 (3.3) | 0 (0) | 0 (0) | ||
AST (%) | ||||||
≤ 2×ULN | 1983 (73.1) | 24 (80.0) | 0.350 | 45 (90.0) | 22 (88.0) | 0.793 |
2-5×ULN | 494 (18.2) | 5 (16.7) | 5 (10.0) | 3 (12.0) | ||
> 5×ULN | 234 (8.6) | 1 (3.3) | 0 (0) | 0 (0) | ||
γ-GT (%) | ||||||
≤ 2×ULN | 1340 (49.4) | 15 (50.0) | 0.378 | 32 (64.0) | 14 (56.0) | 0.434 |
2-5×ULN | 753 (27.8) | 13 (43.3) | 18 (36.0) | 10 (40.0) | ||
> 5×ULN | 518 (22.8) | 2 (6.7) | 0 (0) | 1 (4.0) | ||
ALP (%) | ||||||
≤ 2×ULN | 2294 (84.6) | 22 (73.3) | 0.092 | 41 (82.0) | 19 (76.0) | 0.543 |
2-5×ULN | 358 (13.2) | 7 (23.3) | 9 (18.0) | 6 (24.0) | ||
> 5×ULN | 59 (2.2) | 1 (3.3) | 0 (0) | 0 (0) | ||
Creatinine (%) | ||||||
≤ ULN | 2660 (98.1) | 29 (96.7) | 0.567 | 50 (100.0) | 25 (100.0) | − |
1-1.5×ULN | 35 (1.3) | 1 (3.3) | 0 (0) | 0 (0) | ||
> 1.5×ULN | 16 (0.6) | 0 (0) | 0 (0) | 0 (0) | ||
Anti-coagulation (%) | 14 (0.5) | 1 (3.3) | 0.403 | 0 (0) | 0 (0) | − |
Anti-platelet (%) | 36 (1.3%) | 0 (0) | 1.000 | 0 (0) | 0 (0) | − |
Hemodialysis (%) | 14 (0.5) | 0 (0) | 1.000 | 0 (0) | 0 (0) | − |
Number of passes (%) | ||||||
1 | 660 (24.3) | 2 (6.7) | <0.001 | 4 (8.0) | 2 (8.0) | 1.000 |
2 | 1976 (72.9) | 15 (50.0) | 30 (60.0) | 15 (60.0) | ||
≥ 3 | 75 (2.8) | 13 (43.3) | 16 (32.0) | 8 (32.0) | ||
Comorbidities (%) | 630 (23.2) | 8 (26.7) | 0.659 | 10 (20.0) | 6 (24.0) | 0.690 |
Hypertension | 445 (16.4) | 2 (6.7) | 0.235 | 7 (14.0) | 2 (8.0) | 0.706 |
Diabetes | 238 (8.8) | 5 (16.7) | 0.235 | 8 (16.0) | 3 (12.0) | 0.908 |
Chronic kidney disease | 34 (1.3) | 0 (0) | 1.000 | 1 (2.0) | 0 (0) | 1.000 |
Cerebrovascular disease | 29 (1.1) | 0 (0) | 1.000 | 0 (0) | 0 (0) | − |
Coronary heart disease | 63 (2.3) | 1 (3.3) | 0.510 | 0 (0) | 1 (4.0) | 0.333 |
RBC (×1012/L) | 4.4 (3.9, 5.2) | 3.8 (3.4, 4.6) | 0.002 | 3.9 ± 0.7 | 3.9 ± 0.9 | 0.694 |
Hb (g/L) | 132.0 (119.0, 147.0) | 113.0 (101.0, 138.3) | 0.001 | 119.9 ± 22.3 | 114.0 ± 26.2 | 0.315 |
PLT (×109/L) | 171.0 (127.0, 223.0) | 68.0 (40.0, 96.5) | <0.001 | 101.5 (75.0, 209.5) | 64.0 (38.0, 81.5) | <0.001 |
PT (s) | 11.8 (11.0, 12.6) | 13.7 (13.1, 14.8) | <0.001 | 12.2 (11.3, 13.2) | 13.7 (13.2, 14.9) | <0.001 |
INR | 1.04 (0.98, 1.11) | 1.20 (1.14, 1.29) | <0.001 | 1.10 (1.00, 1.27) | 1.21 (1.16, 1.31) | <0.001 |
FIB (g/L) | 2.3 (1.9, 2.7) | 1.9 (1.6, 2.6) | 0.014 | 2.2 (1.7, 2,8) | 1.8 (1.5, 2.4) | 0.074 |
Ascites (%) | 124 (4.6) | 22 (73.3) | <0.001 | 19 (38.0) | 18 (72.0) | 0.005 |
Complication (%) | 151 (5.6) | 1 (3.3) | 0.896 | 5 (10.0) | 1 (4.0) | 0.652 |
Hepatic hemorrhage | 35 (1.3) | 0 (0) | 1.000 | 2 (4.0) | 0 (0) | 0.550 |
Grade 1 | 21 (0.8) | 0 (0) | − | 1 (2.0) | 0 (0) | − |
Grade 2 | 11 (0.4) | 0 (0) | 1 (2.0) | 0 (0) | ||
Grade 3 | 2 (0.1) | 0 (0) | 0 (0) | 0 (0) | ||
Grade 4 | 1 (0.0) | 0 (0) | 0 (0) | 0 (0) | ||
Abdominal pain | 108 (4.0) | 1 (3.3) | 1.000 | 3 (6.0) | 1 (4.0) | 1.000 |
Grade 1 | 93 (3.4) | 1 (3.3) | 0.690 | 3 (6.0) | 1 (4.0) | − |
Grade 2 | 7 (0.3) | 0 (0) | 0 (0) | 0 (0) | ||
Grade 3 | 8 (0.3) | 0 (0) | 0 (0) | 0 (0) | ||
Gastrointestinal stress | 6 (0.2) | 0 (0) | 1.000 | 0 (0) | 0 (0) | − |
Fever | 2 (0.1) | 0 (0) | 1.000 | 0 (0) | 0 (0) | − |