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Table 3 Assessment of malignant esophageal stenosis before and after chemotherapy

From: Impact of preoperative docetaxel, cisplatin, and 5-fluorouracil (DCF) therapy on degree of malignant esophageal stenosis

  

FP group

(n = 50)

DCF group

(n = 31)

P value

Length of stenosis (cm, mean ± SD)

Before

4.6 ± 1.74

6.0 ± 2.06

*0.003 a

 

After

4.3 ± 1.55

5.3 ± 1.94

*0.012 a

Reduction rate in the stenotic length (%, mean)

 

6.6

10.8

0.298 a

Width of the narrowest portion (cm, mean ± SD)

Before

1.1 ± 0.59

0.8 ± 0.44

*0.030 a

 

After

1.0 ± 0.55

1.0 ± 0.45

0.862 a

Expansion rate in the width of narrowest portion (%, mean)

 

102

127

*0.031 a

Intraluminal stenotic area (cm2, mean ± SD)

Before

6.5 ± 2.73

8.3 ± 3.90

*0.034 a

 

After

5.6 ± 2.40

7.8 ± 4.07

*0.009 a

Stenosis lumen area reduction rate (%, mean)

 

11.1

2.6

0.176 a

SI (mean)

Before

1.47 ± 0.48

1.38 ± 0.39

0.392 a

 

After

1.37 ± 0.47

1.47 ± 0.42

0.353 a

The rate of SI change (%, mean)

 

96

112

*0.038 a

  1. Numbers given as n (%)
  2. SD, standard deviation; SI, stenosis index (intraluminal stenotic area/length of stenosis); FP, 5-fluorouracil and cisplatin; DCF, docetaxel, cisplatin, and 5-fluorouracil;
  3. *P < 0.05
  4. a Student’s t-test