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Table 4 CD34+ % & SDF-1 α mRNA expression and concentration gradient in the 5 study groups

From: Correlation between SDF-1α, CD34 positive hematopoietic stem cells and CXCR4 expression with liver fibrosis in CCl4 rat model

 

Group

One-Way ANOVA

Effect Size

 

Control

4wks CCL4

8 wks CCL4

F

p -value

Partial η2 (a)

Cohen’s f

CD34+ % in blood

(mean±SE)

8.98 ± 0.21

23.72 ± 0.23ab

50.65 ± 0.44a

4549.402

< 0.001

0.998

22.33831

CD34+ % in liver

(mean±SE)

3.1 ± 0.37

35.08 ± 0.41ab

55.05 ± 0.23a

9331.564

<0.001

0.999

31.60696

SDF-1 α mRNA gene expression in bone marrow

(mean±SE)

19.12 ± 0.19

8.62 ± 0.21ab

2.36 ± 0.15a

2044.276

<0.001

0.996

15.77973

SDF-1 α mRNA gene expression in liver

(mean±SE)

1.11 ± 0.004

13.0 ± 0.06ab

19.33 ± 0.19a

6433.868

<0.001

0.999

31.60696

SDF-1 α concentration gradient

(mean±SE)

-18 ± 0.19

4.38 ± 0.18ab

17 ± 0.17a

9480.891

<0.001

0.999

31.60696

  

2wks reversion

4wks reversion

F

p -value

Partial η2 (b)

Cohen’s f

CD34+ % in blood

(mean±SE)

 

37.5 ± 0.50ab

26.37 ± 0.58abc

1508.696

<0.001

0.996

15.77973

CD34+ %

in liver

(mean±SE)

 

42.8 ± 0.46ab

34.57 ± 0.51abc

3789.609

<0.001

0.998

22.33831

SDF-1 α mRNA gene expression in bone marrow

(mean±SE)

 

5.69 ± 0.16ab

8.22 ± 0.26abc

1394.804

<0.001

0.995

14.10674

SDF-1 α mRNA gene expression in liver

(mean±SE)

 

15.04 ± 0.02ab

11.79 ± 0.34abc

1560.472

<0.001

0.996

15.77973

SDF-1 α concentration gradient

(mean±SE)

 

9 ± 0.15ab

4 ± 0.59abc

2048.795

<0.001

0.997

18.23001

  1. Partial η2 (a) is a measure of effect size between the groups (control and 4wks & 8wks CCl4) created by Univariate analysis in a general linear model (GLM).
  2. Partial η2 (b) is a measure of effect size between the groups (control, 8wks CCl4, and 2& 4wks reversion) created by Univariate analysis in a general linear model (GLM).
  3. aSubstantial variation VS control group
  4. bsubstantial variation VS 8wks CCl4 group
  5. csubstantial variation VS 2wks reversion group