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Fig. 3 | BMC Gastroenterology

Fig. 3

From: A novel role for Helicobacter pylori cytotoxin-associated gene A in negative regulation of autophagy in human gastric cells

Fig. 3

mRNA expression and protein levels of autophagic core proteins in AGS cells infected with Helicobacter pylori. A Western blotting analysis of autophagy-related proteins in AGS cells infected with Hp-WT and Hp-ΔcagA. Quantification of ATG5, ATG7, Beclin1, and ULK1 signal intensity (n = 4, mean ± SD, *P < 0.05). B) mRNA expression levels of ATG5 and BECN1 in AGS cells infected with Hp-WT and Hp-ΔcagA analysed using q-RT PCR (n = 6, mean ± SD, *P < 0.05). ATG5, autophagy related 5; Hp-WT, wild-type cagA-positive H. pylori; Hp-ΔcagA, cagA-knockout H. Pylori; q-RT PCR, quantitative reverse transcription-polymerase chain reaction; SD, standard deviation

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BMC Gastroenterology

ISSN: 1471-230X

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