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Table 1 Comparison of baseline characteristics of derivative and validation cohorts

From: Safe discharge for patients admitted for lower gastrointestinal bleeding (LGITB): derivation and validation of a novel scoring system

Variable

Derivative ( n  = 798)

Validation ( n  = 312)

P -value

Clinical demographics

 Gender (n = 1110)

  Female

335 (42.0%)

161 (51.6%)

0.004

  Male

463 (58.0%)

151 (48.4%)

  Age (n = 1110)

66 (IQR 54–77)

69 (IQR 54–79)

0.08

Medical history and medications

  Previous LGITB admission (n = 1110)

131 (16.4%)

57 (18.3%)

0.459

  Presence of hypertension (n = 1110)

381 (47.7%)

136 (43.6%)

0.212

  Presence of diabetes (n = 1110)

619 (77.6%)

241 (77.2%)

0.907

  Presence of ischemic heart disease (n = 1110)

157 (19.7%)

57 (18.3%)

0.594

  Presence of chronic kidney disease (n = 1110)

88 (11.0%)

33 (10.6%)

0.829

  Presence of liver disease (n = 1110)

12 (1.5%)

6 (1.9%)

0.619

  Charlson Score (n = 1110)

3 (IQR 1–4)

3 (IQR 1–5)

0.129

  Usage of antiplatelets (n = 1110)

212 (26.6%)

80 (25.6%)

0.753

  Usage of anticoagulation (n = 1110)

46 (5.8%)

24 (7.7%)

0.235

Signs and symptoms at presentation

  DRE findings of blood (n = 1093)

563 (71.8%)

238 (77.0%)

0.08

  Presence of diarrhea (n = 1108)

108 (13.6%)

48 (15.4%)

0.434

  Presence of abdominal tenderness (n = 1110)

97 (12.2%)

35 (11.2%)

0.664

  Presence of syncope or dizziness (n = 1052)

219 (28.9%)

87 (29.7%)

0.788

Vital signs and laboratory results at presentation

  SBP at triage (n = 1109)

130 (IQR 115–149)

131.0 (IQR 117–151.8)

0.415

  DBP at triage (n = 1109)

76 (IQR 69–85)

77 (IQR 68.3–84.8)

0.904

  HR at triage (n = 1109)

83 (IQR 73–95)

85 (IQR 75–97)

0.068

  Initial Hb (n = 1110)

11.9 (IQR 9.9–13.4)

11.5 (IQR 9.13–13.3)

0.048

  TW count (n = 1110)

8.28 (IQR 6.45–10.7)

8.39 (IQR 6.83–10.8)

0.428

  Platelet count (n = 1110)

254 (IQR 205–313)

262 (IQR 211–315)

0.270

  INR levels (n = 1011)

0.97 (IQR 0.94–1.02)

1.0 (IQR 0.97–1.04)

 < 0.001

  APTT levels (n = 979)

26.8 (IQR 24.9–28.8)

25.9 (IQR 23.6–27.9)

 < 0.001

  Urea levels (n = 1107)

5.30 (IQR 4.10–7.30)

5.55 (IQR 4.10–7.65)

0.209

  Bicarbonate levels (n = 1107)

22.4 (IQR 20.8–24.0)

22.1 (IQR 20.1–23.7)

0.017

  Creatinine levels (n = 1108)

77.0 (IQR 60.0–99.5)

76.0 (IQR 62.0–94.0)

0.793

Aetiology of LGITB (n = 1110)

  Colitis (n = 154)

97 (12.2%)

57 (18.3%)

0.008

  Diverticular disease (n = 376)

270 (33.8%)

106 (34.0%)

0.965

  Haemorrhoids (n = 420)

316 (39.6%)

104 (33.3%)

0.053

  Malignancy (n = 70)

45 (5.6%)

25 (8.0%)

0.144

  Length of stay (n = 1110)

3.0 (IQR 2.0–4.0)

3.0 (IQR 2.0–4.0)

0.299

  Safe discharge (n = 1100)

499 (62.5%)

191 (61.2%)

0.685

  1. Data represented in numbers (%), mean (standard deviation) or median (inter-quartile range)
  2. DRE Digital rectal examination, SBP Systolic blood pressure, DBP Diastolic blood pressure, HR Heart rate, Hb Haemoglobin, TW Total whites, INR International Normalised Ratio, APTT Activated partial thromboplastin time