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Table 5 Univariate and multivariate analyses of risk factors for serious complications in patients over 80 years of age

From: Acute cholecystitis in old adults: the impact of advanced age on the clinical characteristics of the disease and on the surgical outcomes of laparoscopic cholecystectomy

Factor

Multivariate analysis

Multivariate analysis

 

OR (95% CI)

P-value

OR (95% CI)

P-value

Gender

    

Female

1 (ref)

   

Male

1.726 (0.730–4.077)

0.214

  

Charlson age comorbidity index

    

< 7

1 (ref)

   

≥ 7

1.520 (0.486–4.751)

0.472

  

Body mass index, kg/m2

    

> 20

1 (ref)

 

1 (ref)

 

18.5–20.0

1.095 (0.302–3.965)

0.890

-

 

< 18.5

4.078 (1.322–12.580)

0.014

4.254 (1.273–14.221)

0.019

ASA PS classification

    

< 3

1 (ref)

   

≥ 3

1.226 (0.502–2.995)

0.654

  

Previous abdominal surgery

    

No

1 (ref)

   

Yes

1.421 (0.501–4.034)

0.509

  

Severity of acute cholecystitis

    

Mild

1 (ref)

 

1 (ref)

 

Moderate

3.604 (1.366–9.512)

0.010

3.545 (1.282–9.807)

0.015

Severe

4.463 (1.204–16.535)

0.025

3.924 (1.012–15.211)

0.048

WBC, 103/mm3

    

< 18.0

1 (ref)

   

≥ 18.0

0.862 (0.244–3.038)

0.817

  

Albumin, g/dL

    

≥ 2.5

1 (ref)

 

1 (ref)

 

< 2.5

6.711 (1.852–24.318)

0.004

4.414 (1.136–17.153)

0.032

Total bilirubin, mg/dL

    

< 2.0

1 (ref)

   

≥ 2.0

1.019 (0.403–2.574)

0.968

  

Creatinine, mg/dL

    

< 2.0

1 (ref)

   

≥ 2.0

3.436 (0.886–13.327)

0.074

  

CRP, mg/dL

    

< 20.0

1 (ref)

   

≥ 20.0

1.795 (0.685–4.702)

0.234

  

EST

    

No

1 (ref)

   

Yes

0.268 (0.061–1.172)

0.080

  

PTGBD

    

No

1 (ref)

   

Yes

0.661 (0.260–1.683)

0.385

  
  1. OR: odds ratio; CI: confidence interval; ASA PS: American Society of Anesthesiologists physical status; WBC: white blood cell; CRP: C-reactive protein; EST: endoscopic sphincterotomy; PTGBD: percutaneous transhepatic gallbladder drainage