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Fig. 3 | BMC Gastroenterology

Fig. 3

From: Biochemical and histopathological evidence for beneficial effects of Empagliflozin pretreatment on acetic acid-induced colitis in rats

Fig. 3

Photomicrographs of section of colons from rats stained with H&E. Colon microscopic image of (A) Normal rat with intact epithelial (head arrow) and Mucosal layer (*); (B) AA-induced colitis rats with extensive damage (black arrows) including ulceration; Hyperemia; Necrosis; edema in submucosa, cellular infiltration, and Cellular hyperplasia (C) Pretreatment with EMPA reduced histological alterations induced by AA (4%) in rat colon. (D) Dexa treated rats. Magnification 100×, scale bar 100 μm. (E) Represents the altered pathological scores after induction of UC as compared to AA group and its restoration by EMPA and Dexa treatment. The results were expressed as mean ± SEM (n = 6). #p < 0.05 vs. AA group; ###p < 0.001 vs. AA group. AA: Acetic acid, EMPA: Empagliflozine, Dexa: Dexamethasone

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BMC Gastroenterology

ISSN: 1471-230X

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