Variable | Rivaroxaban n = 52 | Dabigatran n = 42 | P Value |
---|---|---|---|
Age (y), mean (SD) | 55 (14) | 55 (13) | 0.828 |
Sex (male), n (%) | 38 (73) | 23 (55) | 0.111 |
Esophageal varices F1/F2/F3, n (%) | 30/9/1 (32/10/1) | 28/4/1 (30/4/1) | 0.849 |
Beta-blocker therapy, n (%) | 15 (29) | 12 (29) | 0.977 |
Etiology of cirrhosis, n (%) | Â | Â | 0.314 |
 Alcohol | 14 (27) | 6 (14) |  |
 HBV | 28 (54) | 21 (50) |  |
 HCV | 1 (2) | 1 (2) |  |
 Autoimmune | 3 (6) | 8 (19) |  |
 NASH | 2 (4) | 1 (2) |  |
 Other | 4 (8) | 5 (12) |  |
Child–Pugh score, mean (SD) | 7.1 (1.1) | 6.9 (1.2) | 0.284 |
MELD score, mean (SD) | 9.0 (7.0–10.5) | 8.4 (7.4–10.7) | 0.834 |
D-dimer (ug/mL),(IQR) | 1.7 (0.8–3.2) | 2.8 (0.9–5.1) | 0.127 |
INR − median (IQR) | 1.2 (1.1–1.4) | 1.2 (1.1–1.4) | 0.083 |
Total bilirubin (umol/L), mean (SD) | 23 (23) | 22 (20) | 0.667 |
Albumin (g/L), mean (SD) | 29 (5) | 30 (5) | 0.468 |
Creatinine (mmol/L), mean (SD) | 67.2 (18.9) | 65 (17.6) | 0.56 |
GFR (mL/ min), mean (SD) | 104 (23) | 101 (21) | 0.396 |
Platelet (x10^9/L), (IQR) | 126 (63–203) | 179 (66–258) | 0.115 |
Duration of LMWH bridging therapy | 1 (1–2) | 1 (1–2) | 0.615 |
Yerdel classification, n (%) | Â | Â | 0.637 |
 Grade I | 15 (19) | 11 (26) |  |
 Grade II | 11 (21) | 11 (26) |  |
 Grade III | 10 (19) | 12 (27) |  |
 Grade IV | 16 (31) | 8 (11) |  |
Complete occlusive thrombus, n (%) | 12 (23) | 9 (21) | 0.849 |