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Table 1 Characteristics at baseline of patients in the study

From: Establishment and validation of a prognosis nomogram for MIMIC-III patients with liver cirrhosis complicated with hepatic encephalopathy

Variable

Training cohort (n = 434)

Validation cohort (n = 186)

P value

Demographics

 Age, year

54.72 (14.91)

54.79 (11.96)

0.496

 Gender, n(%)

  

0.674

  Men

277 (63.8)

122 (65.6)

 

  Women

157 (36.2)

64 (34.4)

 

 weight, kg

85.00 (26.00)

82.00 (29.00)

0.899

Etiology of cirrhosis

  

0.689

 Alcoholic cirrhosis of liver

257 (59.2%)

111 (59.7%)

 

 Cirrhosis of liver without mention of alcohol

168 (38.7%)

73 (39.2%)

 

 Biliary cirrhosis

9 (2.1%)

2 (1.1%)

 

Firstday vital signs in ICUa

 Mean heart rate, beats/min

87.09 (23.13)

83.67 (22.65)

0.021

 MAP, mmHg

73.75 (15.38)

72.82 (17.35)

0.255

 Mean respiratory rate, breaths/min

17.87 (5.32)

17.52 (4.99)

0.918

 Mean SpO2,%

97.64 (2.78)

97.74 (2.43)

0.721

 Mean temperature, °C

36.60 (0.83)

36.57 (0.83)

0.859

Complication

 Alcohol abuse, n(%)

256 (59.0)

107 (57.5)

0.735

 Chronic pulmonary, n(%)

78 (18.0)

38 (20.4)

0.472

 Cardiac arrhythmias, n(%)

79 (18.2)

32 (17.2)

0.766

 Coagulopathy, n(%)

245 (56.5)

103 (55.4)

0.805

 Congestive heart failure, n(%)

68 (15.7)

29 (15.6)

0.981

 Diabetes, n(%)

123 (28.3)

56 (30.1)

0.656

 Hypertension, n(%)

149 (34.3)

65 (34.9)

0.883

 Renal failure, n(%)

83 (19.1)

44 (23.7)

0.200

First laboratory testsb

 Lactate, mmol/L

2.30 (1.80)

2.20 (1.40)

0.191

 ALT,IU/L

37.00 (39.00)

37.50 (44.00)

0.285

 Albumin, g/dL

2.80 (0.70)

2.80 (0.80)

0.536

 ALP, IU/L

125.00 (87.00)

130.50 (96.00)

0.277

 Anion gap, mEq/L

14.00 (6.00)

15.00 (6.00)

0.594

 AST,IU/L

72.00 (81.00)

72.00 (92.00)

0.790

 Bicarbonate, mEq/L

22.00 (7.00)

21.00 (7.00)

0.324

 Total bilirubin, mg/dL

4.20 (6.70)

4.35 (8.90)

0.910

 Total calcium, mg/dL

8.40 (1.10)

8.40 (1.00)

0.628

 Chloride, mEq/L

103.00 (11.00)

101.00 (10.00)

0.451

 Creatinine, mg/dL

1.30 (1.40)

1.45 (1.70)

0.344

 Magnesium, mg/dL

1.90 (0.50)

2.00 (0.60)

0.155

 Potassium, mEq/L

4.30 (1.20)

4.35 (1.20)

0.057

 Sodium, mEq/L

136.00 (9.00)

134.50 (9.00)

0.169

 Urea Nitrogen, mg/dL

30.00 (32.00)

31.00 (34.00)

0.140

 Hemoglobin, g/dL

10.40 (2.60)

10.25 (2.30)

0.594

 INR

1.80 (0.80)

1.80 (0.70)

0.891

 PLT,K/uL

101.50 (80.00)

97.50 (75.00)

0.831

 PT, sec

18.60 (6.20)

18.10 (5.90)

0.746

 PTT, sec

38.80 (12.60)

39.90 (12.60)

0.530

 RDW,%

17.40 (3.10)

17.00 (3.30)

0.580

 WBC, K/uL

8.50 (6.70)

8.20 (6.80)

0.791

 RBC, m/uL

3.16 (0.82)

3.11 (0.76)

0.643

Therapeutic measure

 Albumin use, n(%)

211 (48.6%)

92 (49.5%)

0.847

 Furosemide use, n(%)

232 (53.5%)

93 (50.0%)

0.430

 PPI use, n(%)

331 (76.3%)

142 (76.3%)

0.984

 PAD, n(%)

226 (52.1%)

89 (47.8%)

0.335

Severity score

 SOFA

9.00 (5.00)

9.00 (5.00)

0.959

 MELD

30.00 (12.64)

30.00 (13.96)

0.556

Others

 Urine Outputc, ml

964.50 (1044.00)

1029.00 (1161.00)

0.878

  1. Categorical variables were presented as frequency (percentage), and continuous variables were presented as median (interquartile)
  2. MAP Mean arterial pressure, SpO2 Blood oxygen saturation, ALT Alanine aminotransferase, AST Aspartate aminotransferase, ALP Alkaline phosphatase, INR International normalized ratio, PT Prothrombin time, PTT Partial thromboplastin time, PLT Platelet, RDW Red cell distribution width, WBC White blood cell count, RBC Red blood cell count, PPI.use Proton pump inhibitors use, PAD Percutaneous abdominal drainage, SOFA Sequential organ failure assessment, MELD Model for end-stage liver disease
  3. aVital signs were calculated as the mean value during the first 24 h since ICU admission of each included patients
  4. bThe laboratory tests recorded the first value after admission
  5. cThe urine output was recorded during the first 24 h in the ICU
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BMC Gastroenterology

ISSN: 1471-230X

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